Antitoxins: novel strategies to target agents of bioterrorism

Nature Reviews. Microbiology
G Jonah A Rainey, John A T Young

Abstract

Never before has there been such a strong possibility that biological agents might be used indiscriminately on civilian populations. This review focuses on the use of antitoxins - antibodies, receptor decoys, dominant-negative inhibitors of translocation, small-molecule inhibitors and substrate analogues - to counteract those biological weapons for which toxins are an important mechanism of disease pathogenesis.

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