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Antitumor activity of [Pt(O,O'-acac)(γ-acac)(DMS)] in mouse xenograft model of breast cancer

Cell Death & Disease

Jan 23, 2014

Antonella MuscellaSanto Marsigliante

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Abstract

The higher and selective cytotoxicity of [Pt(O,O'-acac)(γ-acac)(DMS)] toward cancer cell in both immortalized cell lines and in breast cancer cells in primary cultures, stimulated a pre-clinical study so as to evaluate its therapeutic potential in vivo. The efficacy of [Pt(O,O'-acac)(γ-...read more

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Acrospiroma
Apoptosis, Intrinsic Pathway
Antineoplastic Agents
Malignant Neoplasm of Breast
Pharmacokinetic Aspects
Tumor Cells, Malignant
Breast Carcinoma
Mice, Nude
Pt(O, O'-acac)(gamma-acac)(DMS)
Drug Kinetics
Paper Details
References
  • References20
  • Citations8
12
  • References20
  • Citations8
1

Antitumor activity of [Pt(O,O'-acac)(γ-acac)(DMS)] in mouse xenograft model of breast cancer

Cell Death & Disease

Jan 23, 2014

Antonella MuscellaSanto Marsigliante

PMID: 24457958

DOI: 10.1038/cddis.2013.554

Abstract

The higher and selective cytotoxicity of [Pt(O,O'-acac)(γ-acac)(DMS)] toward cancer cell in both immortalized cell lines and in breast cancer cells in primary cultures, stimulated a pre-clinical study so as to evaluate its therapeutic potential in vivo. The efficacy of [Pt(O,O'-acac)(γ-...read more

Mentioned in this Paper

Acrospiroma
Apoptosis, Intrinsic Pathway
Antineoplastic Agents
Malignant Neoplasm of Breast
Pharmacokinetic Aspects

Related Papers

Paper Details
References
  • References20
  • Citations8
12
  • References20
  • Citations8
1

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