Antiviral activity of an aqueous extract derived from Aloe arborescens Mill. against a broad panel of viruses causing infections of the upper respiratory tract

Phytomedicine : International Journal of Phytotherapy and Phytopharmacology
B Glatthaar-SaalmüllerA Saalmüller

Abstract

A number of antiviral therapies have evolved that may be effectively administered to treat respiratory viral diseases. But these therapies are very often of limited efficacy or have severe side effects. Therefore there is great interest in developing new efficacious and safe antiviral compounds e.g. based on the identification of compounds of herbal origin. Since an aqueous extract of Aloe arborescens Mill. shows antiviral activity against viruses causing infections of the upper respiratory tract in vitro we hypothesised that a product containing it such as Biaron C(®) could have an antiviral activity too. Antiviral activity of Bioaron C(®), an herbal medicinal product consisting of an aqueous extract of Aloe arborescens Mill., Vitamin C, and Aronia melanocarpa Elliot. succus, added as an excipient, was tested in vitro against a broad panel of viruses involved in upper respiratory tract infections. These studies included human adenovirus and several RNA viruses and were performed either with plaque reduction assays or with tests for the detection of a virus-caused cytopathic effect. Our studies demonstrated an impressive activity of Bioaron C(®) against members of the orthomyxoviridae - influenza A and influenza B viruses. Repl...Continue Reading

References

Mar 15, 1990·Annals of Internal Medicine·J A EnglundH H Balfour
Feb 1, 1997·The Journal of Antimicrobial Chemotherapy·K A Cassady, R J Whitley
Oct 23, 1997·Antiviral Research·A SummerfieldA Saalmüller
Jun 9, 2001·Antiviral Research·B Glatthaar-SaalmüllerA Esperester
May 6, 2004·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Erik De Clercq
Sep 10, 2010·Antiviral Research·Yunjeong KimKyeong-Ok Chang
Nov 3, 2010·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·Martin MichaelisJindrich Cinatl
Nov 25, 2011·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·B Glatthaar-SaalmüllerA Saalmüller
Jun 20, 2013·BMC Complementary and Alternative Medicine·Anthony CantatoreSandra D Adams
Jun 10, 2014·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·L Leibovici, M Paul
Jul 24, 2014·São Paulo Medical Journal = Revista Paulista De Medicina·João Toniolo Neto

❮ Previous
Next ❯

Citations

Oct 8, 2016·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Maryam AkaberiSeyed Ahmad Emami
Aug 15, 2019·Phytotherapy Research : PTR·Mohammad K ParvezAli S Alqahtani
Aug 28, 2020·Frontiers in Medicine·Farhana Rumzum BhuiyanMahmudul Hasan
Sep 12, 2019·The American Journal of Chinese Medicine·Jang-Gi ChoiJin Yeul Ma
Dec 31, 2020·Biomolecules·Parvaneh MehrbodSaeid Ghavami

❮ Previous
Next ❯

Methods Mentioned

BETA
enzymatic assay
enzyme-linked immunosorbent assays
ELISA

Software Mentioned

Bioaron

Related Concepts

Related Feeds

Antivirals (ASM)

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

Antiparasitics

Antiparasitics are medications which are indicated for the treatment of parasitic diseases. Discover the latest research on antiparasitics here.

Antivirals

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.