Antiviral Chemistry & Chemotherapy's current antiviral agents FactFile (2nd edition): DNA viruses

Antiviral Chemistry & Chemotherapy
H J Field, Erik De Clercq

Abstract

Although most of the recent attempts to develop new antiviral agents have been focussed on RNA viruses (in particular, HIV and hepatitis C virus), a few new compounds are now awaiting their entry into the field of DNA viruses, particularly poxviruses, such as variola virus, because of the bioterrorist context, and herpesviruses, such as herpes simplex virus and cytomegalovirus, where the market scene has for many years been dominated by acyclovir, penciclovir and ganciclovir and their respective orally bioavailable prodrugs: valaciclovir, famciclovir and valganciclovir. Here, we review the current 'state of the art' with old compounds ready to rotate off and new compounds eagerly awaiting to appear on the continuously evolving scene of antiviral drug development.

References

Dec 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·G B ElionH J Schaeffer
Sep 1, 1978·Science·E HelgstrandB Oberg
Jun 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·E De ClercqR T Walker
Oct 1, 1992·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·M W FriedJ H Hoofnagle
Jul 1, 1988·Antimicrobial Agents and Chemotherapy·R PauwelsE De Clercq
Jul 1, 1981·Antimicrobial Agents and Chemotherapy·H MachidaH Yoshino
Nov 1, 1980·British Medical Journal·E de ClercqP de Somer
Mar 5, 1998·Journal of the American Academy of Dermatology·K R BeutnerJ M Douglas
Apr 3, 1998·Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association·J P LalezariH S Jaffe
Sep 19, 2000·Antimicrobial Agents and Chemotherapy·M D PescovitzF Brown
Dec 20, 2000·Antimicrobial Agents and Chemotherapy·M L BryantJ P Sommadossi
Apr 3, 2002·Nature Medicine·Gerald KleymannHelga Rübsamen-Waigmann
Jul 18, 2002·Antimicrobial Agents and Chemotherapy·George W KoszalkaKaren K Biron
May 6, 2004·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Erik De Clercq
Jul 9, 2004·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Patrick MarcellinHyo-Suk Lee
Jul 23, 2004·Antiviral Chemistry & Chemotherapy·Gerald Kleymann
Jul 5, 2005·Expert Opinion on Investigational Drugs·J TemsamaniP Guinot
Nov 15, 2005·British Journal of Pharmacology·Erik De Clercq, Hugh J Field

❮ Previous
Next ❯

Citations

Jan 25, 2013·Antiviral Chemistry & Chemotherapy·Erik De Clercq
Nov 16, 2011·Antimicrobial Agents and Chemotherapy·Philippe SelhorstGuido Vanham
Nov 17, 2010·Antimicrobial Agents and Chemotherapy·Jocelyne Piret, Guy Boivin

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antivirals

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

Antivirals (ASM)

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

Related Papers

Nature Reviews. Microbiology
Erik De Clercq
Journal of the American Academy of Dermatology
Tricia J BrownStephen K Tyring
© 2022 Meta ULC. All rights reserved