Antiviral treatment of genital herpes

International Journal of STD & AIDS
A Apoola, K Radcliffe

Abstract

A review of the randomized, controlled trials in the literature on the treatment of genital herpes infection with aciclovir, famciclovir and valaciclovir. Common clinical questions encountered by physicians, such as the effect of antivirals on symptoms, healing, aborting attacks and subsequent recurrences, are addressed. There is very little comparative data between the three licensed drugs but the little data that there is shows no difference in efficacy, tolerability and toxicity between aciclovir, valaciclovir or famciclovir when taken orally. Choice of therapy would then depend on convenience of dosing and cost.

Citations

Aug 12, 2006·American Journal of Clinical Dermatology·Stephen TyringKamal Hamed
Dec 1, 2005·Expert Review of Pharmacoeconomics & Outcomes Research·David A Baker
Jun 16, 2005·Expert Review of Anti-infective Therapy·David A Baker
Jul 13, 2006·Current Medical Research and Opinion·Richard WhitleyKamal Hamed
Jul 12, 2005·Antiviral Chemistry & Chemotherapy·Eddy Littler, Bo Oberg

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