PMID: 375375Jan 1, 1979Paper

Antral G- and D-cell counts in chronic renal failure

Scandinavian Journal of Gastroenterology
O CrivelliG Verme


Antral somatostatin- and gastrin-producing cells (D and G cells) were studied in a group of patients with chronic renal failure (CRF) in comparison with a control group. Gastric acid secretion and serum gastrin, phosphate, and parathormone (PTH) levels were also evaluated in every patient. The group with CRF showed a mild increase both in G- and in D-cell denisty. In this group serum phosphate and PTH levels were higher than normal, showing hyperparathyroidism in every patient. A direct correlation was found between G-cell density and parathyroid function in patients with CRF. Hyperparathyroidism, therefore, seems to play a role in the mechanism of increased serum gastrin levels in CRF.


Jan 1, 1977·Scandinavian Journal of Gastroenterology·O CrivelliG Verme
Jun 16, 1973·Lancet·A M ShepherdK G Wormsley
Jan 22, 1972·British Medical Journal·M G KormanJ Hansky
Oct 7, 1972·British Medical Journal·P S VentkateswaranA G Hocken

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