Anxiety Administrated by Dexmedetomidine to Prevent New-Onset of Postoperative Atrial Fibrillation in Patients Undergoing Off-Pump Coronary Artery Bypass Graft

International Heart Journal
Jie ZiQi Tan

Abstract

This study aims to evaluate the effect of dexmedetomidine (DEX) sedation for relieving anxiety and the incidence of atrial fibrillation (AF) after off-pump coronary artery bypass graft (OPCABG).This randomized, double-blind, controlled trial was conducted on 196 patients who underwent OPCABG in Shandong Provincial Hospital from July 2017 to June 2018. The patients were randomly assigned to two groups, intervention of DEX group and Propofol (PROP) group. Episodes of postoperative AF (POAF) were identified within 5 days after OPCABG. Perioperative anxiety status was assessed using Zung's Self-Rating Anxiety Scale (SAS). The baseline demographic and surgical characteristics of the population and other outcome variables were evaluated.We analyzed 62 patients in the DEX group and 61 patients in the PROP group. There was no significant difference in SAS anxiety scores between two groups before surgery (P = 0.104), while SAS had significantly after surgery (P = 0.018). The incidence of POAF in the DEX group was lower than that of the PROP group (16.1% versus 32.8%, P = 0.037), and a total of 30 patients (30/123, 24.4%) manifested POAF after OPCABG. Some univariable predictors of POAF were detected. The conceptual model of mediator ana...Continue Reading

References

Nov 1, 1971·Psychosomatics·W W Zung
Feb 23, 2008·Journal of Psychosomatic Research·Phillip J TullyJohn L Knight
May 9, 2014·Pacing and Clinical Electrophysiology : PACE·Michael EfremidisSpyridon Deftereos
Dec 3, 2014·Journal of Cardiothoracic and Vascular Anesthesia·Di AiUNKNOWN Outcomes Research Consortium
Aug 6, 2015·Dimensions of Critical Care Nursing : DCCN·Hilary K JosephWanda Taylor
May 11, 2016·Circulation. Arrhythmia and Electrophysiology·Padmini SirishNipavan Chiamvimonvat
Sep 23, 2016·Critical Care : the Official Journal of the Critical Care Forum·Xu LiuXiangming Fang
Aug 15, 2017·Journal of Cardiothoracic and Vascular Anesthesia·Joaquín Hernández-PalazónRubén Jara-Rubio
Sep 15, 2017·Journal of the American Heart Association·Lilei YuHong Jiang
Nov 28, 2017·The Annals of Thoracic Surgery·Samuel St-OngeSpencer Melby
Jan 30, 2018·International Heart Journal·Yukiteru Nakayama, Katsuhito Fujiu
May 19, 2018·Journal of Clinical Nursing·Vimala RamooRaveena Rajalachimi R Thinagaran
Apr 26, 2019·International Heart Journal·Do Jung KimYoung-Nam Youn
Jun 18, 2019·International Heart Journal·Xiao LiuKui Hong

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Atrial Filbrillation

Atrial fibrillation refers to the abnormal heart rhythm characterized by rapid and irregular beating of the atria. Here is the latest research.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.