Anxiety and depression in primary Sjögren's syndrome: a cross-sectional study

BMC Psychiatry
Yafei CuiZhifeng Gu

Abstract

Prevalence of anxiety and depression is high in people with Primary Sjögren's syndrome (pSS). However, there are currently no known reported studies about anxiety/depression in pSS patients from China. Our aim was to compare anxiety/depression in pSS patients and healthy controls; to investigate the prevalence of anxiety and/or depression among pSS patients in China; to evaluate its relationship with the disease activity, fatigue, pain, education, ocular surface disease, oral health, swallowing disorders, employment status, European League Against Rheumatism Sjögren's Syndrome Patient Reported Index(ESSPRI) as well as to analyze potential determinants of anxiety and depression. In this study, 160 pSS patients and 170 age- and sex- matched healthy controls were included. Participants completed self-administered questionnaires, Hospital Anxiety and Depression Scale (HADS) and so on. Independent samples t-tests, χ2 analyses and multivariable stepwise logistic regression modeling were used to analyze the data. We found 33.8% pSS patients were anxiety, and 36.9% had depression, which were significantly higher than controls. And there were significant correlations among education, employment status, disease activity, fatigue, ocular ...Continue Reading

References

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Apr 3, 2010·The Journal of Rheumatology·Jiunn-Horng Kang, Herng-Ching Lin
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Nov 25, 2011·European Journal of Oral Sciences·Tone B EngerJanicke L Jensen
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Aug 16, 2014·The Journal of Sexual Medicine·Panagiota AnyfantiStella Douma
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Jun 18, 2017·Psychology, Health & Medicine·Yafei CuiBiyu Shen

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Citations

Feb 6, 2019·Psychiatry and Clinical Neurosciences·Bogna Grygiel-GórniakMariusz Puszczewicz
Sep 13, 2020·International Journal of Rheumatic Diseases·Youngjae ParkSeung-Ki Kwok
Sep 24, 2020·Oral Diseases·Noelia Galiano-CastilloGeorge David Baxter
Jan 20, 2021·Journal of Women's Health·Ana María AlcaldeFrancisco Carmona
Jul 25, 2021·Reumatología Clinica·Iván Posso-OsorioGabriel J Tobón
Jun 25, 2020·Reumatología clinica·Iván Posso-OsorioGabriel J Tobón
Aug 28, 2021·International Journal of Molecular Sciences·Sheng-Dean LuoChing-Shuen Wang

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Methods Mentioned

BETA
ESR

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