Aortic-Brachial Stiffness Mismatch and Mortality in Peritoneal Dialysis Patients

Kidney & Blood Pressure Research
WenHan BaoWen Tang

Abstract

Possible predictive value of aortic-brachial arterial stiffness mismatch assessed by pulse wave velocity PWV ratio in peritoneal dialysis patients' outcomes need to be further elucidated. The aim of this study is to investigate the predictor value of PWV ratio on peritoneal dialysis (PD) patients' outcomes in China. In this longitudinal cohort study, patients who started PD during September 20, 2005, to February 05, 2008, were included. All the patients were followed until January 31, 2018. Aortic-brachial arterial stiffness mismatch was assessed using carotid-femoral pulse wave velocity divided by carotid-radial pulse wave velocity (PWV ratio). A total of 181 incident PD patients were included. The median survival of patients in PWV ratio above median group (4.03 years, 95% CI 4.64-7.99 years) was shorter than that of PWV ratio below median group (10.43 years, 95% CI 9.74-11.12 years, p< 0.001). The cardiovascular mortality rate in PWV ratio above median group were significantly higher than that of PWV below median group (log rank test, p< 0.001). Univariate Cox regression analysis showed that both PWV ratio (HR 2.42, 95% CI 1.80-3.25, p< 0.001) and CF-PWV (HR 1.27, 95% CI 1.16-1.38, p< 0.001) were associated with high patient...Continue Reading

Citations

Mar 20, 2020·Arteriosclerosis, Thrombosis, and Vascular Biology·Shikai Yu, Carmel M McEniery
Mar 12, 2021·Journal of Human Hypertension·Vasilios VaiosVassilios Liakopoulos
Apr 4, 2020·Current Vascular Pharmacology·Panagiotis I GeorgianosVassilios Liakopoulos

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