Aortic involvement in relapsing polychondritis

Joint, Bone, Spine : Revue Du Rhumatisme
Maëlle Le BesneraisIsabelle Marie

Abstract

To assess prevalence of aortic involvement in relapsing polychondritis (RP) patients; to evaluate clinical features and long-term outcome of RP patients exhibiting aortitis, aortic ectasia and/or aneurysm. One hundred and seventy-two RP patients underwent aortic computed tomography (CT)-scan; they were seen in 3 medical centers. Eleven patients (6.4%) had aortic involvement, occurring within a median time of 2 years after RP diagnosis. CT-scan showed isolated aortitis (n=2); the 9 other patients exhibited: aortitis and aortic aneurysm (n=2) or ectasia (n=1), isolated aortic aneurysm (n=4) or ectasia (n=2); aortic localizations were as follows: thoracic (n=6), abdominal (n=2), thoracic and abdominal (n=4) aorta. Patients exhibited: resolution (n=3) improvement (n=3), stabilization (n=4) or deterioration (n=1) of aortic localization. Five patients experienced recurrence of aortic localization; one patient died of aortic abdominal aneurysm rupture. Predictive factors of death related to aortic complications were: aortitis on CT-scan, higher median levels of erythrocyte sedimentation rate. Predictive parameters of aortic relapses were: aortitis on CT-scan and involvement of the abdominal aorta. This study underlines that aortic inv...Continue Reading

Citations

Feb 7, 2020·Rheumatology·Tsuyoshi ShiraiHideo Harigae
Nov 8, 2018·RMD Open·Simona RednicLaurent Arnaud
Nov 27, 2019·Rheumatology International·Mustafa ErdoganVedat Hamuryudan
Jan 10, 2020·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Masatoshi HottaHiroyuki Yamashita
Dec 3, 2020·The Journal of Rheumatology·David P D'Cruz, Marcela A Ferrada
Nov 19, 2018·Joint, Bone, Spine : Revue Du Rhumatisme·Philippe MertzLaurent Arnaud

❮ Previous
Next ❯

Related Concepts

Related Feeds

Aortic Aneurysm

An aortic aneurysm is the weakening and bulging of the blood vessel wall in the aorta. This causes dilatation of the aorta, which is usually asymptomatic but carries the risk of rupture and hemorrhage. Find the latest research on aortic aneurysms here.

Aneurysm

Aneurysms are outward distensions or bulges that occurs in a weakened wall of blood vessels. Discover the latest research on aneurysms here.

Cardiac Aneurysm

Aneurysm refers to a bulge of the wall or lining of a vessel commonly occurring in the blood vessels at the base of the septum or within the aorta. In the heart, it usually arises from a patch of weakened tissue in a ventricular wall, which swells into a bubble filled with blood. Discover the latest research on cardiac aneurysm here.