Aortic isthmus blood flow in fetuses of diabetic mothers

Prenatal Diagnosis
Paulo ZielinskyAlexandre Antonio Naujorks

Abstract

To test the hypothesis that the aortic isthmus flow index (IFI) is lower in fetuses of diabetic mothers than in fetuses of nondiabetic mothers. We performed a cross-sectional observational study to assess the IFI in fetuses, with (n = 13) and without (n = 37) myocardial hypertrophy, of mothers with diabetes mellitus and in fetuses of nondiabetic mothers (n = 23). Analysis of variance and Tukey test were used to assess differences among the groups. There were no differences in maternal or gestational age among the groups. In fetuses of diabetic mothers, the mean IFI in fetuses with myocardial hypertrophy was 1.19 ± 0.06, and in fetuses without it was 1.18 ± 0.09. The mean IFI in fetuses of nondiabetic mothers was 1.32 ± 0.07 (P < 0.001). The IFI in fetuses of diabetic mothers is lower than in fetuses of nondiabetic mothers, possibly as a result of a decreased left ventricular compliance.

References

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Citations

Jun 16, 2012·Revista Española De Cardiología·Constancio Medrano-Lopez, Jean-Claude Fouron
Mar 27, 2012·Early Human Development·Paulo Zielinsky, Antonio Luiz Piccoli

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