Oct 22, 2016

Aortic Valve Calcification and the Risk of dementia: A Population-Based Study

Journal of Alzheimer's Disease : JAD
Frank J WoltersM Arfan Ikram


The association of aortic valve calcification (AVC) with dementia remains unknown. In 2,428 non-demented participants from the population-based Rotterdam Study, we investigated the association of CT-assessed AVC with risk of dementia and cognitive decline. AVC was present in 33.1% of the population. During a median follow-up of 9.3 years, 160 participants developed dementia. We found no association between presence of AVC and risk of all-cause dementia [hazard ratio (HR): 0.89 (95% confidence interval (CI):0.63;1.26)]. Presence of AVC was not associated with cognitive decline on any of the cognitive tests, nor with a measure of global cognition.

  • References10
  • Citations1
  • References10
  • Citations1


Mentioned in this Paper

Senile Paranoid Dementia
Aortic Valve Disorder
Incidence Studies
Aortic Valve Stenosis
Cognition Disorders
AVC brand of sulfanilamide
Tomography, X-Ray Computerized Axial
Impaired Cognition

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