Aortic valve fenestrations: a review

Porto Biomedical Journal
Caixia ZhuJosé Pedro L Nunes

Abstract

Aortic valve fenestrations (AVFs) seem to be relatively common; however, their impact in human heart disease is not entirely clear. A review was carried out to assess all scientific literature on human patients related to AVFs, as described in the published literature. The search was conducted on 2 different databases, Medline (PubMed), and ISI Web of Knowledge. Fifty-five reports were under analysis. Autopsy studies showed AVFs to be present in 55.9% of individuals studied in such studies. They occur more frequently in men and, in general, their frequency increases with age. Although common, fenestrations rarely cause regurgitation; however, they may play an important role in the pathophysiology of some cases of severe aortic regurgitation. AVFs have been described in patients with Down syndrome and Marfan syndrome, in patients with bicuspid or quadricuspid valves, and in patients with myxomatous valvular degeneration. Echocardiographic assessment of aortic regurgitation seems to have limitations in the diagnosis of valvular fenestrations. Fenestrations of the aortic valve are very common and are associated with certain clinical conditions. It is unknown if AVFs play any role in the current epidemic of aortic valve disease. Fu...Continue Reading

References

Aug 1, 1992·The Thoracic and Cardiovascular Surgeon·S AoyagiK Oishi
Jan 1, 1985·Anatomy and Embryology·J M HurleM A Fernandez-Teran
Jun 1, 1971·Circulation·J B CarterJ E Edwards
Mar 1, 1967·British Heart Journal·A Pomerance
Mar 21, 2000·Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology·H BlaszykW D Edwards
May 1, 1956·Circulation·L J MCCORMACK, W L PROUDFIT
Apr 1, 1958·The American Journal of Medicine·B FRIEDMAN, B M HATHAWAY
Oct 1, 1959·Circulation·C P BAILEYJ F URICCHIO
Nov 1, 1963·American Heart Journal·F I MARCUSG A EWY
May 1, 2004·Circulation Journal : Official Journal of the Japanese Circulation Society·Kazuya AkiyamaMasatoshi Tsuda
Sep 25, 2008·Asian Cardiovascular & Thoracic Annals·Yujiro KawanishiYutaka Okita
Jan 24, 2009·The Annals of Thoracic Surgery·Clifton C ReadeJoseph E Bavaria
Aug 21, 2009·The Journal of Thoracic and Cardiovascular Surgery·Hans-Joachim SchäfersDiana Aicher
Nov 26, 2009·The Annals of Thoracic Surgery·Paul Urbanski
Jul 24, 2012·The Annals of Thoracic Surgery·Manabu YamasakiKohei Kawazoe
Sep 10, 2014·Journal of Cardiac Surgery·Khaled D AlgarniJoseph F Maalouf
Mar 1, 1996·Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology·A P LeeW J Keon
Dec 1, 2012·Journal of Echocardiography·Kazumi AkasakaNaoyuki Hasebe
Sep 3, 2016·European Heart Journal Cardiovascular Imaging·Shankho GanguliBijoy Khandheria
Oct 18, 2016·Circulation Journal : Official Journal of the Japanese Circulation Society·Keitaro MaharaShuichiro Takanashi
Mar 11, 2017·General Thoracic and Cardiovascular Surgery·Seiji MatsukumaKiyoyuki Eishi
Sep 10, 2017·European Heart Journal·Helmut BaumgartnerUNKNOWN ESC Scientific Document Group
May 11, 2012·Journal of Cardiology Cases·Akiko IshigeMasahiro Endo
Jul 6, 2019·Mayo Clinic Proceedings·Li-Tan YangPatricia A Pellikka

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