Aortic valve replacement with the minimal extracorporeal circulation (Jostra MECC System) versus standard cardiopulmonary bypass: a randomized prospective trial

The Journal of Thoracic and Cardiovascular Surgery
J P RemadiC Tribouilloy

Abstract

We prospectively evaluated a newly introduced minimal extracorporeal circulation system (Jostra MECC System; Jostra AG, Hirrlingen, Germany) for aortic valve surgery. In a prospective, randomized study, 100 patients underwent aortic valve replacement either with standard cardiopulmonary bypass (n = 50, group B) or with the MECC System (n = 50, group B). The myocardial protection and the left vent were identical for the two groups. The intrapericardial suction device was never used (only the cell salvage device was used) to reduce the air-blood contact area. No significant differences were noted in patient characteristics and operative data between groups. Operative mortality (<30 days) was 2% for group A and 4% for group B (difference not significant). From the preoperative period to the postoperative period, the increase in C-reactive protein was significantly higher for group B (P <.001). The postoperative troponin I level was significantly lower in group A (mean 4.65 +/- 2.9 microg/L at 24 hours) than in group B (8.2 +/- 4.4 microg/L, P <.03). On the other hand, the MECC System was associated with platelet preservation. Renal function was better preserved and the neurologic event rate was significantly lower for the MECC gro...Continue Reading

References

Jun 1, 1995·The Annals of Thoracic Surgery·J P SchönbergerJ J Hoffmann
Feb 1, 1993·The Annals of Thoracic Surgery·J ButlerS Westaby
May 20, 1999·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·A LieboldD E Birnbaum
Nov 11, 1999·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·H P Wendel, G Ziemer
Aug 16, 2001·The Thoracic and Cardiovascular Surgeon·G NollertR A Jonas
Jan 5, 2002·Shock·G Nollert, B Reichart
Sep 26, 2002·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Yves FromesOlivier M Bical
Dec 4, 2002·Artificial Organs·Masanori FujitaTadaaki Maehara

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Citations

Aug 12, 2005·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Norihiko ShiiyaKeishu Yasuda
Jul 3, 2013·Interactive Cardiovascular and Thoracic Surgery·Aziz U MominJon R Anderson
Feb 13, 2009·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Fabienne AreggerFelix J Frey
Jan 27, 2011·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Leanne HarlingThanos Athanasiou
Jun 5, 2013·Journal of Cardiothoracic Surgery·Aziz MominGianni Angelini
Apr 17, 2007·Critical Care : the Official Journal of the Critical Care Forum·Marco Ranucci, Giuseppe Isgrò
Jan 21, 2009·Interactive Cardiovascular and Thoracic Surgery·Anastasia AlevizouJames David Park
Jan 1, 2007·Multimedia Manual of Cardiothoracic Surgery : MMCTS·Mattia GlauberJamshid Karimov
Aug 23, 2011·Scandinavian Cardiovascular Journal : SCJ·Alaaddin YilmazGeoffrey T L Kloppenburg
Nov 23, 2013·The Annals of Thoracic Surgery·David W YaffeeEugene A Grossi
May 25, 2011·The Journal of Thoracic and Cardiovascular Surgery·Marco RanucciUNKNOWN European Association of Cardiothoracic Anaesthesiologists
Sep 25, 2009·The Journal of Thoracic and Cardiovascular Surgery·Alberto ZangrilloGiovanni Landoni
Mar 28, 2009·The Annals of Thoracic Surgery·Marco RanucciSimonetta Brozzi
Feb 24, 2009·The Annals of Thoracic Surgery·Alaadin YilmazGeoffrey T L Kloppenburg
Feb 3, 2009·The Journal of Thoracic and Cardiovascular Surgery·Marc P SakwaArlen R Holter
Mar 28, 2006·The Annals of Thoracic Surgery·Cesare BeghiTiziano Gherli
Jan 30, 2007·The Annals of Thoracic Surgery·Alessandro CastiglioniOttavio Alfieri
Mar 19, 2014·Journal of cardiology·Nikolaos G BaikoussisEfstratios Apostolakis
Nov 9, 2007·Orvosi hetilap·László GöbölösLajos Papp
Aug 20, 2016·Expert Review of Cardiovascular Therapy·Ioannis Dimarakis
Feb 21, 2006·Annales Françaises D'anesthèsie Et De Rèanimation·C BaufretonF Pinaud
Mar 28, 2012·Perfusion·J SjatskigG T L Kloppenburg
Jun 29, 2010·Perfusion·Nathan CurtisSunil K Ohri
Mar 9, 2007·Artificial Organs·Ingo KutschkaWolfgang Harringer

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