Aortic valve-sparing in 37 patients with Marfan syndrome: midterm results with David operation

The Annals of Thoracic Surgery
Alberto FortezaJose Cortina

Abstract

We reviewed our experience with aortic valve-sparing operations in Marfan syndrome during last 5 years. Between March 2004 and June 2009, 94 patients with aortic root aneurysms underwent valve-sparing operations. Of these, 37 (68% male) were diagnosed with Marfan syndrome, according to the Ghent diagnostic criteria. Mean age was 30 +/- 10 years (range, 11 to 59 years). Moderate/severe aortic regurgitation was present in 13%, and the mean diameter of the Valsalva sinuses was 50 +/- 4 mm (range, 42 to 62 mm). The David V modification was performed in the last 28 patients. Additional procedures were mitral valve repair in 6, tricuspid valve repair in 3, closure of septal atrial defect in 2, and closure of a patent foramen ovale in 13. Mean follow-up was 27 +/- 16 months (range, 1 to 61 months). There were no in-hospital deaths and no major adverse outcomes. One patient required implantation of a mechanical prosthesis during the same procedure because of moderate aortic regurgitation. One late death occurred. No patients required reoperation. In the last follow-up, 23 patients did not have aortic regurgitation, 12 had grade I, and 1 had grade II. No thromboembolic complications have been documented, and 97% of the patients are free...Continue Reading

References

Apr 13, 1972·The New England Journal of Medicine·J L MurdochV A McKusick
Jul 29, 2006·The Journal of Thoracic and Cardiovascular Surgery·Tirone E DavidManjula Maganti
Jan 30, 2007·The Annals of Thoracic Surgery·Tirone E DavidManjula Maganti
Mar 5, 2009·The Journal of Thoracic and Cardiovascular Surgery·Irina V VolguinaUNKNOWN Aortic Valve Operative Outcomes in Marfan Patients study group
Apr 22, 2009·The Annals of Thoracic Surgery·Duke E CameronVincent L Gott

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Citations

Feb 15, 2013·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Alberto FortezaJose Cortina
Dec 14, 2011·Interactive Cardiovascular and Thoracic Surgery·Hideyuki ShimizuRyohei Yozu
Oct 16, 2012·The Annals of Thoracic Surgery·Markus LiebrichTimo Weimar
May 10, 2011·Revista española de cardiología·Alberto FortezaJosé Cortina
Sep 2, 2011·Annals of Thoracic and Cardiovascular Surgery : Official Journal of the Association of Thoracic and Cardiovascular Surgeons of Asia·Hideyuki Shimizu, Ryohei Yozu
Mar 27, 2021·Journal of the Chinese Medical Association : JCMA·Wen-Po FanPi-Chang Lee

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