PMID: 12788660Jun 6, 2003Paper

Aortomyoplasty: hemodynamics and comparison to the intraaortic balloon pump

The Journal of Surgical Research
J T SherwoodBrian L Cmolik

Abstract

Aortomyoplasty (AMP), a procedure in which the latissimus dorsi muscle (LDM) is wrapped around the aorta and stimulated during diastole, is a potential method of chronic counterpulsation. Counterpulsation by the intraaortic balloon pump (IABP) is a proven treatment for ischemic coronary syndrome and heart failure but cannot be used chronically. This study examined the long-term potential of a unique AMP configuration and compared its performance to the IABP. AMP was done using a wringer configuration (AMP-W) in nine dogs. Six and 12 months later, acute hemodynamic augmentation was evaluated by measuring differences in mean diastolic aortic pressure (mDAP), peak left ventricular pressure (pLVP), and the endocardial viability ratio (EVR) between stimulated and unstimulated beats. The diastolic augmentation obtained by AMP-W at 6 months and by AMP-W and IABP at 12 months was statistically significant. Additionally, the enhancements in EVR (16.1 +/- 4.3%), mDAP (8.6 +/- 2.5%), and pLVP (-1.8 +/- 1.0%) at 6 months were similar to those in EVR (19.1 +/- 5.2%), mDAP (13.1 +/- 3.6%), and pLVP (-0.8 +/- 1.3%) at 12 months. Most importantly, the augmentation obtained by AMP-W at 12 months was similar to that of the IABP: EVR (17.1 +/- 5....Continue Reading

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Citations

Mar 10, 2010·Regenerative Medicine·Hutan AshrafianThanos Athanasiou
Dec 7, 2007·Bulletin of Environmental Contamination and Toxicology·Maria Soledad Astorga-EspañaSandra Guerrero
Feb 11, 2011·Journal of Human Hypertension·R A RalstonK Z Walker
Mar 7, 2007·Expert Review of Cardiovascular Therapy·Tomasz Timek, Kai Ihnken

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