AP-1 Takes Centre Stage in Enhancer Chromatin Dynamics

Trends in Cell Biology
Pedro Madrigal, Kaur Alasoo

Abstract

Recent studies involving induced pluripotent stem cell (iPSC) reprogramming in mice and monocyte-to-macrophage differentiation in humans have revealed a role for the transcription factor (TF) activator protein 1 (AP-1) in chromatin accessibility. Enhancer selection may be determined not only by cell type-specific sets of TFs but also by broadly expressed ones like AP-1.

Citations

Oct 3, 2018·Endocrinology·V Praveen ChakravarthiM A Karim Rumi
Sep 12, 2020·Biochemical Society Transactions·Simon J CookPamela A Lochhead
Dec 5, 2020·Nature Communications·Jose A Guerrero-MartínezJose C Reyes
Apr 30, 2019·Biochimica Et Biophysica Acta. Reviews on Cancer·Fabienne BejjaniIsabelle Jariel-Encontre
Jun 28, 2021·Molecular Biology and Evolution·Arne SahmSteve Hoffmann
Oct 6, 2021·Cell Reports·François KuonenAnthony E Oro

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