PMID: 8991092Dec 1, 1996Paper

AP-2-containing clathrin coats assemble on mature lysosomes

The Journal of Cell Biology
Linton M TraubS Kornfeld

Abstract

Coat proteins appear to play a general role in intracellular protein trafficking by coordinating a membrane budding event with cargo selection. Here we show that the AP-2 adaptor, a clathrin-associated coat-protein complex that nucleates clathrin-coated vesicle formation at the cell surface, can also initiate the assembly of normal polyhedral clathrin coats on dense lysosomes under physiological conditions in vitro. Clathrin coat formation on lysosomes is temperature dependent, displays an absolute requirement for ATP, and occurs in both semi-intact cells and on purified lysosomes, suggesting that clathrin-coated vesicles might regulate retrograde membrane traffic out of the lysosomal compartment.

References

Jan 1, 1990·Annual Review of Cell Biology·B M Pearse, M S Robinson
Jan 1, 1989·Annual Review of Cell Biology·S Kornfeld, I Mellman
Dec 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·D J ChinF M Brodsky
May 1, 1986·The Journal of Cell Biology·J Lippincott-Schwartz, D M Fambrough
Jun 1, 1985·The Journal of Cell Biology·V LewisI Mellman
May 1, 1968·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·E Holtzman, R Dominitz
Nov 1, 1967·The Journal of Cell Biology·D S Friend, M G Farquhar
Apr 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·L BeguinotI Pastan
Nov 1, 1995·The Journal of Cell Biology·L J Page, M S Robinson
Nov 1, 1993·The Journal of Cell Biology·L M TraubS Kornfeld
Dec 1, 1993·The Journal of Cell Biology·M N SeamanM S Robinson
Oct 1, 1993·Trends in Biochemical Sciences·J P Luzio, G Banting
Jun 1, 1993·The Journal of Cell Biology·J HeuserM Clarke
Dec 1, 1995·Cell·J A WhitneyI Mellman
Jan 1, 1996·The Journal of Cell Biology·W StoorvogelH J Geuze
Mar 15, 1996·Science·R Schekman, L Orci

❮ Previous
Next ❯

Citations

Sep 3, 1999·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·R HeilkerP Crottet
Jul 13, 2001·European Journal of Immunology·H SchneiderC E Rudd
Jun 6, 2000·Advanced Drug Delivery Reviews·C T Okamoto
Aug 28, 1998·Current Opinion in Cell Biology·R Le Borgne, B Hoflack
Dec 24, 2002·Trends in Cell Biology·Owen PornillosWesley I Sundquist
May 14, 1999·Trends in Cell Biology·M G Roth
Apr 16, 2002·Molecular Biology of the Cell·Martin SachseJudith Klumperman
Jul 1, 2005·Molecular Biology of the Cell·Katy Janvier, Juan S Bonifacino
Oct 10, 2008·Molecular Biology of the Cell·Peter A KeyelLinton M Traub
Dec 12, 1997·European Journal of Biochemistry·M JadotR Wattiaux
Nov 1, 2001·Annual Review of Cell and Developmental Biology·F M BrodskyD E Wakeham
Jul 20, 2012·BMC Veterinary Research·Jörg RohdeHanns-Joachim Rziha
Sep 17, 2002·Biological & Pharmaceutical Bulletin·Kunizo AraiShoji Ohkuma
Apr 12, 2012·Haematologica·Ganesan KeerthivasanJohn D Crispino
Dec 21, 2005·Proceedings of the National Academy of Sciences of the United States of America·Alexander UngewickellPhilip W Majerus
Feb 7, 1998·Proceedings of the National Academy of Sciences of the United States of America·A SchweizerJ Rohrer
Aug 4, 1999·Proceedings of the National Academy of Sciences of the United States of America·L M TraubD H Fremont
Apr 19, 2003·Proceedings of the National Academy of Sciences of the United States of America·T-G IversenK Sandvig
Jul 12, 2011·Annual Review of Microbiology·César G PruccaHugo D Luján
Sep 23, 1997·The Journal of Cell Biology·M A WestM S Robinson
Mar 22, 2000·The Journal of Cell Biology·I MartinezN W Andrews
Sep 28, 2007·Traffic·Bernd SchröderAndrej Hasilik
Dec 18, 2012·The FEBS Journal·Li XiangWim Van den Ende
May 10, 2013·Plant Signaling & Behavior·Ed EtxeberriaJavier Pozueta-Romero
Jul 12, 2016·Nature Cell Biology·Maria Giovanna De LeoMaria Antonietta De Matteis
Oct 22, 2016·Annals of Neurology·Joan Y W LiuMaria Thom

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Trends in Cell Biology
F M Brodsky
The Journal of Cell Biology
F SimpsonM S Robinson
Biochemical and Biophysical Research Communications
Y SaiS Ohkuma
© 2022 Meta ULC. All rights reserved