PMID: 2487632Jan 1, 1989Paper

APB selectively reduces visual responses in goldfish to high spatiotemporal frequencies

Visual Neuroscience
P J DeMarcoM K Powers

Abstract

Visual responses of goldfish to rotating square-wave gratings were recorded before and after intraocular injection of 2-amino-4-phosphonobutyric acid (APB). High doses of APB reduced the rate of optokinetic nystagmus (OKN) to a relatively high spatial frequency grating moving at a high temporal frequency. Responses to a low spatial frequency grating were not altered, nor were responses to the higher spatial frequency when it rotated slowly. The effects of APB were transient and lasted no longer than 3 d. We conclude that APB reduces OKN to high spatiotemporal frequencies in goldfish.

Citations

Apr 12, 2000·Progress in Neurobiology·H Nakagawa, N Matsumoto
Sep 30, 2010·Proceedings of the National Academy of Sciences of the United States of America·Peter H Schiller
May 1, 1991·Proceedings of the National Academy of Sciences of the United States of America·P J DeMarcoM K Powers
Sep 1, 1990·Documenta Ophthalmologica. Advances in Ophthalmology·P Guité, P Lachapelle
Dec 31, 2002·Vision Research·Hans Maaswinkel, Lei Li
Jun 27, 2007·Visual Neuroscience·Amy E Lindsey, Maureen K Powers

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