PMID: 28496094May 13, 2017Paper

Apical Hypertrophic Cardiomyopathy: Case Report and Literature Review

The American Journal of Case Reports
Tanya DoctorianBao Do

Abstract

BACKGROUND Apical hypertrophic cardiomyopathy (ApHCM) is a relatively rare form of hypertrophic cardiomyopathy that predominantly affects the apex of the left ventricle and typically has a nonobstructive physiology. Its variable presentation and clinical course render ApHCM a commonly delayed or missed diagnosis. CASE REPORT A 53-year-old Caucasian woman presented with chronic progressive chest pain. She was initially started on treatment for acute coronary syndrome. Diagnosis of ApHCM was initially missed on echocardiography, but made on subsequent cardiac catheterization and cardiac MRI. She improved clinically with metoprolol, had a work-up for implantable cardioverter-defibrillator placement, and was referred for genetic testing. CONCLUSIONS Despite earlier studies suggesting a more benign clinical course of ApHCM, recent studies report increased morbidity and mortality, which is comparable to the prognosis of other variants of hypertrophic cardiomyopathy such as hypertrophic obstructive cardiomyopathy. Thus, when formulating a differential diagnosis for chest pain, it is important to include structural heart disease including apical and other variants of hypertrophic cardiomyopathy as part of that differential, as appropri...Continue Reading

References

Feb 19, 2002·Journal of the American College of Cardiology·Maria J ErikssonHarry Rakowski
Nov 12, 2003·The American Journal of Cardiology·Hiroaki KitaokaBarry J Maron
Feb 27, 2013·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Kavitha MuthiahChristopher S Hayward
Jul 28, 2016·Medical Science Monitor Basic Research·Mostafa SamakAlexander Weymann

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Citations

Oct 15, 2018·Journal of the Royal Army Medical Corps·Leanne Jane Eveson, A Williams
Apr 5, 2019·BMC Cardiovascular Disorders·Uzochukwu IbeSabeena Arora
Feb 26, 2021·Case Reports in Cardiology·Nathan ZaherM Chadi Alraies
Jul 25, 2021·Annales de cardiologie et d'angéiologie·A V F ChavesB Markman-Filho

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