Apical temporal lobe resection; "tailored" hippocampus-sparing resection based on presurgical evaluation data

Acta neurochirurgica
Alaa Eldin ElsharkawyAlois Ebner

Abstract

It is the aim of epilepsy surgery in patients with lesional epilepsy for the surgeon to not only remove the lesion itself, but also the epileptogenic zone. Here, we report our experience with a modified temporal resection technique confined to the apical temporal lobe, i.e., sparing the hippocampal formation in patients with epileptogenic lesions in the anterior part of the temporal lobe. This apical temporal lobe resection (aTLR) includes tailored lesionectomy, amygdalectomy, and resection of the mesial structures only in the apex of the temporal lobe. This paper presents our surgical technical details and the outcome of aTLR. Between 2001 and 2008, aTLR was performed in 61 patients. All patients underwent comprehensive presurgical evaluation including video-EEG monitoring, magnetic resonance imaging (MRI), and neuropsychological testing. All patients had a lesion in the apex of the temporal lobe and a normal hippocampus as seen in MRI, as well as intact memory functions in neuropsychological examination. There were 33 males (54.1%) and 28 females (45.9%). The mean age in years at epilepsy onset was 20.2 ± 13.4, the mean age at epilepsy surgery was 32.1 ± 11.9, the mean preoperative epilepsy duration was 11.8 ± 8.8 years and t...Continue Reading

References

Nov 1, 1991·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·W Feindel, T Rasmussen
Nov 1, 1989·Archives of Neurology·J G Cairncross, N J Laperriere
Dec 1, 1982·Annals of Neurology·W T BlumeJ C Kaufmann
Jan 1, 1993·Journal of Neurosurgery·P J KirkpatrickC E Polkey
Dec 1, 1996·Current Opinion in Neurology·J G Villemure, N de Tribolet
Sep 17, 1998·Epilepsia·H LüdersE Wyllie
Aug 4, 2001·The New England Journal of Medicine·S WiebeUNKNOWN Effectiveness and Efficiency of Surgery for Temporal Lobe Epilepsy Study Group
Aug 8, 2001·The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry·J Engel
Aug 18, 2001·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·S K KimB K Cho
Aug 22, 2001·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·F BartolomeiP Chauvel
Aug 23, 2001·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·F WendlingP Chauvel
Aug 28, 2001·Brain : a Journal of Neurology·F Rosenow, H Lüders
Jan 5, 2002·Neurosurgery Clinics of North America·André Palmini, Hans O Lüders
Nov 27, 2002·Journal of Neurosurgery·Hans ClusmannChristian E Elger
Apr 10, 2003·Acta Neuropathologica·Ales F AliashkevichIngmar Blümcke
Dec 2, 2004·Epilepsia·Louis MaillardFabrice Bartolomei
Jun 17, 2008·Brain : a Journal of Neurology·Fabrice BartolomeiFabrice Wendling
Oct 9, 2008·Stereotactic and Functional Neurosurgery·Goksemin AcarKim J Burchiel
Nov 26, 2008·Journal of Neurosurgery·Alaa Eldin ElsharkawyAlois Ebner

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Citations

Dec 18, 2013·Epilepsia·André PalminiVinicius Duval Silva
Jul 2, 2015·The Cochrane Database of Systematic Reviews·Siobhan WestRichard Newton
Jun 27, 2019·The Cochrane Database of Systematic Reviews·Siobhan WestRichard Newton
Jan 31, 2020·Acta neurochirurgica·Andrew C VivasFernando L Vale
Dec 29, 2020·Epilepsy & Behavior : E&B·Lilach GoldsteinMichael R Sperling
Feb 12, 2021·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Hsiang-Yu YuChien Chen

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