PMID: 1195658Jun 15, 1975Paper

Aplastic anemia-a preleukemic stage (author's transl)

Klinische Wochenschrift
K M KoeppenH Gerhartz

Abstract

In a group of 44 patients with primary and secondary aplastic anemia, four (9%) developed an acute leukemia. Cytological changes that pointed to a preleukemia were not observed during the preleukemic stage. The possibility is discussed whether a aplastic anemia and a preleukemia can be distinguished by cytological, cytochemical and cytogenetic tests, by agar-culture technique, liquid-culture and determination of reverse transcriptase.

References

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