Apnea in Preterm and Term Infants After Deep Sedation and General Anesthesia

Hospital Pediatrics
Tamika RozemaCheri D Landers

Abstract

Determine the incidence of apnea in preterm and term infants after deep sedation (DS) compared with general anesthesia (GA). A retrospective chart review was performed on infants who underwent elective DS or GA from January 2008 to December 2013, were <60 weeks postmenstrual age if preterm or <50 weeks postmenstrual age if term, and were monitored for apnea as inpatients after DS or GA. Gestational age, postmenstrual age, chronologic age, anesthetic and sedative medications, procedure indication, and postsedation events were collected. There were 61 DS encounters (24 preterm and 37 term) and 175 GA encounters (120 preterm and 55 term) that met inclusion criteria. No recorded apneic events in either preterm or term infants were recorded after DS. After GA, 1.7% of infants had apneic events (2.5% preterm and 0 term; P = .57 versus DS). All events occurred within 2 hours of monitoring in recovery. None of the infants had apnea after DS. Rates from the literature would suggest that 2 to 6 of the preterm DS subjects should have experienced postsedation apnea. Sampled GA subjects had a rate of 2.5% in preterm infants exhibiting apnea after GA. Although the post-DS apnea rate is lower than what has been previously published, the small...Continue Reading

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Citations

May 31, 2018·Hospital Pediatrics·Patricia D ScherrerPradip P Kamat
Dec 24, 2020·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Alessandra PreziosiFrancesco Macchini

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