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APOE is a correlate of phenotypic heterogeneity in Alzheimer disease in a national cohort

Neurology

Nov 8, 2019

Sandra WeintraubM-Marsel Mesulam

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Abstract

To compare the proportion of APOE ε4 genotype carriers in aphasic vs amnestic variants of Alzheimer disease (AD). The proportion of APOE ε4 carriers was compared among the following 3 groups: (1) 42 patients with primary progressive aphasia (PPA) and AD pathology (PPA/AD) enrolled in th...read more

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Alzheimer's Disease
Autopsy
Drug Carriers
Memory
Neocortex
Medial
Logistic Regression
Primary Progressive Aphasia (Disorder)
Subtype (Attribute)
Cohort
1
1
3
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APOE is a correlate of phenotypic heterogeneity in Alzheimer disease in a national cohort

Neurology

Nov 8, 2019

Sandra WeintraubM-Marsel Mesulam

PMID: 31704790

DOI: 10.1212/wnl.0000000000008666

Abstract

To compare the proportion of APOE ε4 genotype carriers in aphasic vs amnestic variants of Alzheimer disease (AD). The proportion of APOE ε4 carriers was compared among the following 3 groups: (1) 42 patients with primary progressive aphasia (PPA) and AD pathology (PPA/AD) enrolled in th...read more

Mentioned in this Paper

Alzheimer's Disease
Autopsy
Drug Carriers
Memory
Neocortex
1
1
3

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