PMID: 440024Apr 1, 1979Paper

Apoproteins in association with Intralipid incubations in rat and human plasma

Lipids
S F Robinson, S H Quarfordt

Abstract

Intralipid was incubated with rat and human plasma and examined for changes in lipid and aproprotein composition. Upon incubation in rat plasma, Intralipid acquired an apoprotein complement similar to that found in chylomicrons following plasma incubation or in chylomicrons after alimentary lipemia. Since the apoproteins of lipoproteins probably govern their metabolism, these results suggest that Intralipid and chylomicrons undergo similar metabolic fates. This pattern is characterized by a predominance of Apo E (the arginine-rich apoprotein) and Apo C. Incubation of Intralipid with human plasma showed the uptake of Apo A-I and Apo A-IV as well. Density fractionation of the plasma into separate lipoprotein classes identification of high density lipoprotein as the major apoprotein donor to the Intralipid. When rat lipoprotein-free plasma (delta greater than 1.21) was incubated with Intralipid, a different apoprotein pattern appeared in the particles of Sf greater than 400 depending on whether the entire Intralipid preparation or only the Sf greater than 400 fraction alone was incubated. The difference consisted of a virtual total absence of the arginine-rich protein on the Sf greater than 400 particles in whole Intralipid incuba...Continue Reading

References

Jul 17, 1978·Biochimica Et Biophysica Acta·S F Robinson, S H Quarfordt
Apr 1, 1976·Proceedings of the National Academy of Sciences of the United States of America·T SataJ P Kane
May 1, 1976·Proceedings of the National Academy of Sciences of the United States of America·P S RoheimG G Pinter
Sep 1, 1955·The Journal of Clinical Investigation·R J HAVELJ H BRAGDON
Mar 1, 1959·The Journal of Experimental Medicine·A SCANU, I H PAGE
Nov 1, 1964·Clinica Chimica Acta; International Journal of Clinical Chemistry·J BOBERG, L A CARLSON
Jan 1, 1965·The American Journal of Clinical Nutrition·J M IaconoL P Wendel

❮ Previous
Next ❯

Citations

Jul 14, 1994·Biochimica Et Biophysica Acta·J FérézouA C Bach
Oct 29, 1979·Biochemical and Biophysical Research Communications·E Polz, G M Kostner
Jan 1, 1981·The International Journal of Biochemistry·A Cryer
Jan 1, 1996·Progress in Lipid Research·A C BachA Frey
Apr 20, 2001·Advanced Drug Delivery Reviews·P C RensenT J van Berkel
Jul 1, 1995·The Journal of Experimental Medicine·T E ReadJ H Rapp
Mar 1, 1980·The Journal of Clinical Investigation·F ShelburneS Quarfordt
May 1, 1982·The Journal of Clinical Investigation·S H QuarfordtB Schirmer
Jan 1, 1983·Progress in Lipid Research·D QuinnR L Jackson
Jun 14, 1985·Biochimica Et Biophysica Acta·T G Redgrave, R C Maranhao
Apr 1, 1982·Journal of Pharmaceutical Sciences·K J WidderB Sears
Nov 28, 2012·The Journal of Allergy and Clinical Immunology·Jianing LiErik R M Eckhardt
Aug 1, 1996·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·H HedemanR H Müller
Mar 1, 1988·JPEN. Journal of Parenteral and Enteral Nutrition·U Julius, W Leonhardt
Sep 1, 1984·JPEN. Journal of Parenteral and Enteral Nutrition·R H JuddR J Deckelbaum
Nov 1, 1983·Arteriosclerosis : an Official Journal of the American Heart Association, Inc·M R TaskinenI Tulikoura
Apr 25, 2008·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Leonardo MagnoniJean-Michel Weber
Feb 10, 1999·The American Journal of Physiology·N S Kumar, C M Mansbach
Sep 1, 1995·Infection and Immunity·T van der PollS F Lowry

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.