PMID: 9160509DOI: 10.1016/s0966-842x(97)01044-5May 1, 1997Paper
Apoptosis as a proinflammatory event: what can we learn from bacteria-induced cell death?
Trends in Microbiology
A Zychlinsky, P J Sansonetti
Abstract
Infection of cells by some pathogenic bacteria triggers host cell apoptosis. Bacteria-induced apoptosis appears to promote an inflammatory response that causes tissue damage and further bacterial colonization. Shigella pathogenesis offers a paradigm for the role of apoptosis in bacterial infections.
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Apoptosis
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