PMID: 9004082Nov 1, 1996Paper

Apoptosis in lymph nodes in acute African swine fever

Journal of Comparative Pathology
L CarrascoM A Sierra

Abstract

This paper reports apoptosis of lymph-node lymphocytes in swine experimentally inoculated with a virulent African swine fever (ASF) virus isolate (Malawi '83). Apoptosis was observed in both compartments of cortical tissue, but was more intense in diffuse lymphoid tissue (T area). Lymphopenia detected in peripheral blood was associated with T-lymphocyte depletion. No evidence of ASF virus replication was observed in lymphocytes in the lymph nodes studied. This finding, together with the high rate of virus replication recorded in macrophages in diffuse lymphoid tissue as compared with the low rate recorded for lymphoid follicles, suggests a mechanism for the induction of apoptosis related to virus replication in cells of the mononuclear phagocyte system.

References

Nov 1, 1977·The Journal of General Virology·R C WardleyF Hamilton
Jan 1, 1977·Archives of Virology·R C Wardley, P J Wilkinson
Jul 10, 1992·Science·L MeyaardF Miedema
Aug 1, 1992·Zentralblatt für Veterinärmedizin. Reihe B. Journal of veterinary medicine. Series B·A FernandezM A Sierra
Apr 1, 1991·Immunology Today·J C Ameisen, A Capron
Jun 1, 1991·Immunological Reviews·P GolsteinJ D Young
Feb 1, 1990·The Journal of General Virology·P J GriebelL A Babiuk
Feb 1, 1988·Virus Research·I C PanM Shimizu
Apr 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·T M FolksA S Fauci
Dec 1, 1994·Veterinary Immunology and Immunopathology·K M Lam, A C Vasconcelos
Sep 1, 1995·The Journal of General Virology·J C Gómez-VillamandosM A Sierra
Jul 1, 1994·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·J PérezM A Sierra
Jul 1, 1994·The Journal of General Virology·A C Vasconcelos, K M Lam
Jan 1, 1993·Cellular Immunology·G MiglioratiC Riccardi

❮ Previous
Next ❯

Citations

Jan 1, 2004·Veterinary Immunology and Immunopathology·L MandrioliP S Marcato
Oct 31, 2002·Veterinary Immunology and Immunopathology·F J SalgueroJ C Gómez-Villamandos
Aug 10, 2001·Current Opinion in Microbiology·E R Tulman, D L Rock
Feb 5, 2013·Virus Research·J C Gómez-VillamandosL Carrasco
Nov 10, 2012·Virus Research·Sandra BlomeMartin Beer
Jan 30, 2007·Research in Veterinary Science·M Fernández de MarcoJ C Gómez-Villamandos
Jun 23, 2004·Veterinary Immunology and Immunopathology·Linda K DixonFuquan Zhang
May 17, 2005·Journal of Comparative Pathology·F J SalgueroJ C Gómez-Villamandos
Dec 3, 2014·Journal of Comparative Pathology·J M Sánchez-VizcaínoL Carrasco
Mar 4, 2000·Laboratory Investigation; a Journal of Technical Methods and Pathology·T W GeisbertP B Jahrling
Aug 1, 2020·Frontiers in Veterinary Science·Bui Thi To NgaVan Phan Le
Sep 27, 2020·Transboundary and Emerging Diseases·Uda Zahli IzzatiRyoji Yamaguchi
Nov 19, 1997·The Veterinary Record·J PérezJ Martín de las Mulas

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.