Abstract
Treatment of human peripheral blood lymphocytes with heat shock, ionising radiation, bleomycin, etoposide, or hydrogen peroxide induced morphological evidence of apoptosis that was associated with the appearance of 50 Kb double-stranded DNA fragments. The apoptotic response elicited by the above agents, with the exception of hydrogen peroxide, was also paralleled by the formation of internucleosomal DNA fragments. This effect of hydrogen peroxide, however, appeared to be confined to human lymphocytes, since apoptosis induced by the oxidant in U937 cells was in fact associated with DNA laddering.
Citations
Mar 1, 1997·Cell Proliferation·D CoradiniG Di Fronzo
Dec 22, 1998·European Journal of Cell Biology·L Qi, K H Sit
Jun 29, 2011·Environmental Toxicology·Delu ZhangYongding Liu
Jun 2, 2009·Microscopy Research and Technique·Sabrina BurattiniElisabetta Falcieri
Jun 12, 2001·Experimental Cell Research·M MariniG G Poirier
Dec 10, 1999·Journal of the American College of Cardiology·R P Mason
Apr 2, 1998·Experimental Cell Research·M Marini, D Musiani
May 18, 1999·Experimental Cell Research·L M MielnickiB B Asch
Mar 21, 2015·Molecular and Biochemical Parasitology·Marjorie FullertonMinu Chaudhuri
Feb 1, 1997·Redox Report : Communications in Free Radical Research·M MariniR L Levine
Apr 1, 2000·Addiction Biology·J MilosevićS Ruzdijić
Jan 15, 1999·Arteriosclerosis, Thrombosis, and Vascular Biology·P J BestA Lerman
Sep 4, 1999·In Vitro Cellular & Developmental Biology. Animal·T H Dunnebacke, K H Walen
Apr 11, 2000·Anti-cancer Drugs·P ShrivastavaP Ranjan
Mar 5, 2002·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Maurizio BrigottiSimonetta Sperti
Jul 10, 2001·The Journal of Biological Chemistry·V Sée, J P Loeffler
Nov 24, 1999·Journal of Biochemical and Molecular Toxicology·S E RoughtR Y Chuang
Jan 29, 2002·Free Radical Research·M G BattelliF Stirpe
Feb 11, 2000·Annals of the New York Academy of Sciences·L Benítez-Bribiesca, P Sánchez-Suárez
Jun 2, 2000·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·H SawadaS Shimohama
May 7, 2002·Biochemical Pharmacology·Marlene Jimenez Del Rio, Carlos Velez-Pardo