PMID: 1200662Dec 1, 1975Paper

Apparently normal skin in lepromatous leprosy: histopathological findings

Archives of Dermatology
T H ReaN E Levan

Abstract

Biopsy specimens of apparently uninvolved skin from 34 patients with lepromatous leprosy were studied histologically. Bacilli were found in 30 of 31 specimens from clinically polar or near-polar lepromatous patients but not in the three from nonpolar patients. A predominantly perivascular distribution of infiltrate and bacilli is consistent with a hematogenous spread of infection. Subclinical, diffuse lepromatous leprosy is found in patients with nodular lesions and may precede the development of nodules. Study of apparently uninvolved skin may be helpful in classifying patients, in interpreting immunologic responses, and in elucidating the natural history of the illness.

Citations

Jan 1, 1990·International Journal of Dermatology·V N Sehgal, Joginder
Mar 15, 2006·International Journal of Dermatology·Mohammad A El-DaroutiMona R E Abdel-Halim
Jul 1, 1984·International Journal of Dermatology·B C Hirsh, W C Johnson
May 20, 2015·Journal of the American Academy of Dermatology·Aurélia HennEve Maubec

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