Appendicitis in preschool aged children: Regression analysis of factors associated with perforation outcome

Journal of Pediatric Surgery
William BonadioPeter Homel

Abstract

Apply multivariate regression analysis to determine the significance of clinical variables for perforation outcome of a large series of preschool aged children with appendicitis. Retrospective case review of 180 consecutive children<5 years of age diagnosed with appendicitis during an 8-year period. This age group accounted for only 9% of all cases of pediatric appendicitis at our institution during the study period. Perforation rate was inversely proportional to patient age, occurring in 100% aged<1 year, 91% ages 1-2 years, 76% ages 2-3 years, 73% ages 3-4 years, and 57% ages 4-5 years. Risk for perforation increased proportionately with duration of symptoms, ranging from 48% when<1 day vs 84% when>1 day; and 93% when>2 days. One-quarter with perforation had a prior recent medical evaluation with an alternative diagnosis rendered preappendicitis diagnosis. The mean duration of hospitalization was four times longer in those with perforation [8 days] vs no perforation [2 days]. Univariate analysis showed each of the following factors was significantly associated with perforation outcome: younger patient age, female gender, prior medical visit<48 hours of appendicitis diagnosis, symptom duration, presence of fever, and presence ...Continue Reading

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Citations

Mar 29, 2016·Journal of Pediatric Surgery·Justin B MahidaPeter C Minneci
Mar 2, 2017·Pediatric Emergency Care·Susan C Lipsett, Richard G Bachur
Nov 5, 2016·Pediatric Emergency Care·Yagnaram RavichandranJennifer H Chao
Sep 5, 2019·Journal of Paediatrics and Child Health·Marcos Prada-AriasJosé R Fernández-Lorenzo
Jul 28, 2020·Clinical Pediatrics·Dena LowingGrace Kim
Jun 27, 2019·Revista paulista de pediatria : orgão oficial da Sociedade de Pediatria de São Paulo·Belén AneirosAndrés Gómez
Jul 21, 2020·Surgery Research and Practice·Abhinav TotapallyBalagangadhar R Totapally
Jan 13, 2021·Anales de pediatría : publicación oficial de la Asociación Española de Pediatría (A.E.P.)·Leire BonillaJavier Benito
Mar 24, 2021·Journal of Pediatric Surgery·Kristy Schwartz, Margaret Nguyen
Apr 16, 2021·Radiología·C Sangüesa-Nebot, R Llorens-Salvador
May 18, 2021·Frontiers in Pediatrics·Ricards MarcinkevicsJulia E Vogt
Aug 14, 2021·Journal of Indian Association of Pediatric Surgeons·M S Vinod KumarAnil Malik
Aug 31, 2021·ANZ Journal of Surgery·Brodie M ElliottChristopher Harmston

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