Appetite during the recovery phase of critical illness: a cohort study

European Journal of Clinical Nutrition
Judith L MerriweatherTimothy S Walsh

Abstract

Reduced appetite is a recognised physiological symptom in survivors of critical illness. While reduced appetite has been reported by patients after intensive care unit (ICU) discharge, quantification using visual analogue scales (VAS) has not been previously performed, and follow-up duration has been limited. We aimed to describe appetite scores in ICU survivors during the first 3 months after ICU discharge and explore association with systemic inflammation. Secondary analysis of data collected in a complex rehabilitation intervention trial (RECOVER). A subgroup of 193 patients provided specific consent for inclusion in the blood sampling sub-study during consent for the main study. We studied appetite using a VAS; serum C-reactive protein (CRP); interleukin-1β and interleukin-6 (IL-1β and IL-6); and hand-grip strength. Median (interquartile range) score on 0-10 appetite VAS was 4.3 (2.0-6.5) 1 week after ICU discharge, improving to 7.1 (4.6-8.9) by 3 months (mean difference 1.7 (0.9-2.4), p < 0.01). Number of days spent in an acute hospital following an intensive care stay was associated with poorer appetite scores (p = 0.03). CRP concentration and appetite were significantly associated at 1 week after ICU discharge (p = 0.01)...Continue Reading

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Citations

Aug 28, 2018·Current Opinion in Clinical Nutrition and Metabolic Care·Danielle E BearZudin A Puthucheary
Jan 25, 2020·Current Opinion in Clinical Nutrition and Metabolic Care·Emma J RidleyMarianne J Chapman
Dec 4, 2019·JBI Database of Systematic Reviews and Implementation Reports·Louise AlbrichMary Hickson
Jul 4, 2020·The British Journal of Nutrition·Maryam PourhassanRainer Wirth
Aug 3, 2020·Current Opinion in Clinical Nutrition and Metabolic Care·Jennifer R A Jones, David M Griffith
Aug 11, 2020·JPEN. Journal of Parenteral and Enteral Nutrition·Loïc RougierAnne-Françoise Rousseau
Jul 28, 2020·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Lesley L MoiseyMarina Mourtzakis
Jan 31, 2020·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Emmanuel BesnierVincent Compère
Jan 5, 2021·Current Opinion in Clinical Nutrition and Metabolic Care·Morgan K NienowSarah J Peterson
Nov 19, 2020·Nutrients·Marjorie FadeurAnne-Françoise Rousseau

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Methods Mentioned

BETA
enzyme-linked immunosorbent assay

Software Mentioned

RECOVER

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