Application of 3D Printing for Patient-Specific Silicone Stents: 1-Year Follow-Up on 2 Patients

Respiration; International Review of Thoracic Diseases
Thomas R GildeaMichael S Machuzak

Abstract

Managing complex benign airway disease is a major challenge in interventional pulmonology. Airway stent placement can result in complications due to a variety of factors, including poor fit of the stent in the airway. We report the 1-year outcome of 2 patients with airway disease caused by granulomatosis with polyangiitis (Wegener's) affecting the left main bronchus and secondary carina. These patients had not responded to systemic therapy or standard bronchoscopic techniques and had complications with commercially available airway stents. We describe a first-in-human, clinical experience to address these issues. Using computed tomography (CT) imaging and 3D printing technology, we generated and implanted patient-specific silicone airway stents to address airway disease. 3D patient-specific stent prescription was created using a CT scan of the patient's chest and a proprietary software package originally developed for orthopedic surgical planning. Silicone stents were manufactured and implanted. Observation for > 1 year after implantation compared to the 6 months prior to patient-specific stent implant were compared for the number, clinically required stent changes, procedure time, and general clinical improvement per usual sta...Continue Reading

Citations

Mar 5, 2019·Journal of Bronchology & Interventional Pulmonology·Sameer K AvasaralaThomas R Gildea
Jun 27, 2019·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·M Schweigert
Feb 6, 2020·American Journal of Respiratory and Critical Care Medicine·Gerard J CrinerFelix J Herth
Mar 13, 2020·Respirology : Official Journal of the Asian Pacific Society of Respirology·Nicolas GuibertHervé Dutau
Nov 5, 2019·Chest·Momen M WahidiLonny Yarmus
Nov 20, 2020·European Respiratory Review : an Official Journal of the European Respiratory Society·Antoni Rosell, Grigoris Stratakos
Feb 17, 2021·American Journal of Therapeutics·Abhinav Agrawal
Apr 29, 2020·The Journal of Thoracic and Cardiovascular Surgery·Wei HuangZhongmin Wang

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