Application of a LC-MS/MS method for multi-mycotoxin analysis in infant formula and milk-based products for young children commercialized in Southern Brazil

Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes
Karina M TononVildes M Scussel

Abstract

An analytical method based on liquid chromatography-tandem mass spectrometry (LC-MS/MS) was validated and applied for the analysis of aflatoxin M1 (AFM1), ochratoxin A (OTA) and deoxynivalenol (DON) in infant formula and milk-based products for young children commercialized in Brazil. A total of 38 samples were evaluated, including 12 infant formula, 14 follow-on formula and 12 samples of milk-based products. AFM1 was detected in 12 (32%) samples, and seven (18%) samples contained AFM1 levels above the method limit of quantification in a concentration range between 0.013 and 0.067 ng mL-1 (0.026 ± 0.019). Two samples of milk-based products exceeded the maximum level (ML) fixed by the European Union for AFM1 in baby foods, however, all samples were in agreement with the levels established by the Brazilian regulation. OTA and DON were not detected in any of the analyzed samples.

References

May 19, 2005·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·L K Sørensen, T H Elbaek
Oct 10, 2008·Pediatrics·Laurence M Grummer-StrawnSara B Fein
Apr 1, 2009·International Journal of Molecular Sciences·Irena Kralj Cigić, Helena Prosen
Aug 26, 2011·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Wael F El-TrasAhmed A Tayel

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Citations

Dec 19, 2020·Comprehensive Reviews in Food Science and Food Safety·Bianca Figueiredo de Mendonça PereiraBernardete Ferraz Spisso

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Methods Mentioned

BETA
AFM
enzyme linked immuno sorbent assay

Software Mentioned

Analyst®

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