PMID: 9637007Jun 24, 1998Paper

Application of an automated HS-GC method in partition coefficient determination for xylenes and ethylbenzene in rat tissues

Chemosphere
P KumarathasanI Chu

Abstract

An automated static head space-gas chromatography method was used in the determination of partition coefficients (Kd) for the xylene isomers and ethylbenzene in blood, brain, muscle, kidney, liver and fat of Sprague Dawley rats. Since homogenization resulted in the potential loss of analytes from tissue samples, unhomogenized samples were used. With a few exceptions, tissue:air Kd values were independent of the concentrations of the analytes, singly or as a mixture. The tissue:blood Kd values were determined. For each tissue and analyte, the value obtained for each analyte concentration was within +/- 10% of the mean value calculated for the entire concentration range.

References

Sep 1, 1978·Scandinavian Journal of Work, Environment & Health·J Engström, R Bjurström
Jun 1, 1990·Toxicology and Applied Pharmacology·C W LamD L Pierson
Apr 1, 1989·Bulletin of Environmental Contamination and Toxicology·K J FreundtR J Federsel
Mar 15, 1989·Toxicology and Applied Pharmacology·M L GargasM E Andersen
Aug 1, 1988·British Journal of Industrial Medicine·G Johanson, B Dynésius
Dec 1, 1986·Bulletin of Environmental Contamination and Toxicology·K G RömerK J Freundt
Feb 1, 1987·Toxicology and Applied Pharmacology·M E AndersenR H Reitz
Sep 1, 1980·British Journal of Anaesthesia·Y C PangD E Brooks
Sep 30, 1984·Toxicology and Applied Pharmacology·E ElovaaraH Vainio

❮ Previous
Next ❯

Citations

Oct 22, 2015·Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·UNKNOWN Bekanntmachung des Umweltbundesamtes
Oct 6, 2010·Toxicology Mechanisms and Methods·G JoshiJ W Fisher

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Pharmacological Research : the Official Journal of the Italian Pharmacological Society
T KanekoA Sato
International Archives of Occupational and Environmental Health
J Y JangH K Chung
British Journal of Anaesthesia
P J FranksP R Jones
Xenobiotica; the Fate of Foreign Compounds in Biological Systems
G D LoizouM W Anders
© 2022 Meta ULC. All rights reserved