PMID: 26320452Sep 1, 2015Paper

Application of Bayesian Multilevel Space-Time Models to Study Relative Risk of Esophageal Cancer in Iran 2005-2007 at a County Level

Asian Pacific Journal of Cancer Prevention : APJCP
Sedigheh RastaghiBehzad Mahaki

Abstract

Reported age standardized incidence rates for esophageal cancer in Iran are 0.88 and 6.15 for females and males, at fifth and the eighth ranks, respectively, of cancers overall. The present study aimed to map relative risk using more realistic and less problematic methods than common estimators. In this ecological investigation, the studied population consisted of all esophageal cancer patients in Iran from 2005 to 2007. The Bayesian multilevel space-time model with three levels of county, province, and time was used to measure the relative risk of esophageal cancer. Analyses were conducted using R package INLA. The total number of registered patients was 7,160. According to the results, the three-level model with adjustment for risk factors of physical activity and smoking had the best fit among all models .The overall temporal trend was significantly increasing. At county level, Ahar, Marand, Salmas, Bojnoord, Saghez, Sarakhs, Shahroud and Torbatejam had the highest relative risks. Physical activity was found to have significant direct association with risk of developing esophageal cancer. Given to great variation across geographical areas, many different factors affect the incidence of esophageal cancer. Conducting further s...Continue Reading

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Citations

Jun 15, 2019·International Journal of Preventive Medicine·Mehran RostamiBehzad Mahaki
Jun 15, 2019·International Journal of Preventive Medicine·Sedigheh RastaghiAli Soleimani
Apr 11, 2019·International Journal of Preventive Medicine·Vahid AhmadipanahmehrabadiBehzad Mahaki
Sep 17, 2021·Journal of Cancer Research and Therapeutics·Fatemeh Sadat AsgarianNeda Amori

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