Application of capillary zone electrophoresis for separation of water-soluble gold monolayer-protected clusters

Electrophoresis
Chung Keung LoMartin M F Choi

Abstract

An effective capillary electrophoretic technique for separating samples of negatively charged, polydisperse, water-soluble gold monolayer-protected cluster (Au MPC) protected by monolayers of N-acetyl-L-cysteine has been developed. The separation mechanisms of the Au MPC in CZE suggest that the larger core sizes Au MPC emerge first from the capillary. The electrophoretic separation depends on pH, buffer concentration, and organic modifiers. The addition of aliphatic alcohols to the run buffer can improve the separation of Au MPC by reducing the EOF and changing the selectivity between the Au MPCs. The enhancement of resolution is attributed to the more significant difference in the charge-to-size ratio between the Au MPCs. The run buffer containing 20 v/v % ethanol provides the best separation for water-soluble Au MPC. Our proposed CE method provides a powerful tool to evaluate and separate the water-soluble Au MPC products.

References

Mar 29, 2000·Accounts of Chemical Research·A C TempletonR W Murray
Oct 31, 2002·Journal of the American Chemical Society·Jocelyn F HicksRoyce W Murray
Jan 30, 2003·Analytical Chemistry·Victoria L JimenezRoyce W Murray
Sep 18, 2004·Analytical Chemistry·Yang SongRoyce W Murray
Jul 15, 2005·Analytical Chemistry·Rachel R Peterson, David E Cliffel
Feb 8, 2006·Langmuir : the ACS Journal of Surfaces and Colloids·Sven E Eklund, David E Cliffel
Apr 18, 2006·Analytical Chemistry·Martin M F ChoiRoyce W Murray
Aug 31, 2006·Journal of Chromatography. a·Fu-Ken LiuTieh-Chi Chu
Sep 13, 2006·The Journal of Chemical Physics·Dean A EckhoffEnrico Gratton
Oct 31, 2008·Talanta·Natalia G VanifatovaRainer Wennrich

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Citations

Feb 15, 2011·Analytical and Bioanalytical Chemistry·Petr S FedotovBoris Ya Spivakov
May 30, 2009·Journal of Separation Science·Noumie Surugau, Pawel L Urban
Dec 8, 2009·Electrophoresis·Andrei R Timerbaev
Jun 3, 2015·Electrophoresis·Lizhen LiuMartin M F Choi
Feb 26, 2010·Langmuir : the ACS Journal of Surfaces and Colloids·Wenting ZhaoI-Ming Hsing
Dec 20, 2018·Analytical Chemistry·Stefan Knoppe, Pascal Vogt
Feb 15, 2011·Langmuir : the ACS Journal of Surfaces and Colloids·Zhenghua TangGangli Wang

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