Application of Diagnostic Algorithms for Heart Failure With Preserved Ejection Fraction to the Community.

JACC. Heart Failure
Senthil SelvarajScott D Solomon

Abstract

This study sought to describe characteristics and risk of adverse outcomes associated with the H2FPEF and HFA-PEFF scores among participants in the community with unexplained dyspnea. Diagnosing heart failure with preserved ejection fraction (HFpEF) can be challenging. The H2FPEF and HFA-PEFF scores have recently been developed to estimate the likelihood that HFpEF is present among patients with unexplained dyspnea. The study included 4,892 ARIC (Atherosclerosis Risk In Communities) study participants 67 to 90 years of age at visit 5 (2011 to 2013) without other common cardiopulmonary causes of dyspnea. Participants were categorized as asymptomatic (76.6%), having known HFpEF (10.3%), and having tertiles of each score among those with ≥moderate, self-reported dyspnea (13.1%). The primary outcome was heart failure (HF) hospitalization or death. Mean age was 75 ± 5 years, 58% were women, and 22% were black. After a mean follow-up of 5.3 ± 1.2 years, rates of HF hospitalization or death per 1,000 person-years for asymptomatic and known HFpEF were 20.7 (95% confidence interval [CI]: 18.9 to 22.7) and 71.6 (95% CI: 61.6 to 83.3), respectively. Among 641 participants with unexplained dyspnea, rates were 27.7 (95% CI: 18.2 to 42.1), 4...Continue Reading

References

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Citations

Jan 4, 2021·European Heart Journal·Héctor BuenoJohann Bauersachs
Feb 27, 2021·European Journal of Heart Failure·Frederik H VerbruggeBarry A Borlaug
Apr 13, 2021·Circulation·Barry A Borlaug, Michael D Nelson
Sep 22, 2020·Journal of Cardiac Failure·Erwan DonalWojciech Kosmala
Mar 13, 2021·Current Opinion in Cardiology·Peder L MyhreScott D Solomon
May 31, 2021·Heart Failure Clinics·Morten Sengeløv, Tor Biering-Sørensen
Jun 29, 2021·Frontiers in Cardiovascular Medicine·Dmitry Abramov, Purvi Parwani
Jul 5, 2021·The Journal of Thoracic and Cardiovascular Surgery·Seung Hun LeeYoung Tak Lee
Aug 28, 2021·European Heart Journal·Theresa A McDonaghUNKNOWN ESC Scientific Document Group
Dec 22, 2021·The Korean Journal of Internal Medicine·Koichi EgashiraKenichi Tsujita

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