PMID: 15248587Jul 14, 2004Paper

Application of discrete data consistency conditions for selecting regularization parameters in PET attenuation map reconstruction

Physics in Medicine and Biology
Vladimir Y PaninChristian J Michel

Abstract

Simultaneous emission and transmission measurement is appealing in PET due to the matching of geometrical conditions between emission and transmission and reduced acquisition time for the study. A potential problem remains: when transmission statistics are low, attenuation correction could be very noisy. Although noise in the attenuation map can be controlled through regularization during statistical reconstruction, the selection of regularization parameters is usually empirical. In this paper, we investigate the use of discrete data consistency conditions (DDCC) to optimally select one or two regularization parameters. The advantages of the method are that the reconstructed attenuation map is consistent with the emission data and that it accounts for particularity in the emission reconstruction algorithm and acquisition geometry. The methodology is validated using a computer-generated whole-body phantom for both emission and transmission, neglecting random events and scattered radiation. MAP-TR was used for attenuation map reconstruction, while 3D OS-EM is used for estimating the emission image. The estimation of regularization parameters depends on the resolution of the emission image controlled by the number of iterations in...Continue Reading

References

Nov 22, 1997·IEEE Transactions on Medical Imaging·A WelchG T Gullberg
May 8, 1998·Physics in Medicine and Biology·J NuytsL Mortelmans
Oct 26, 1999·IEEE Transactions on Medical Imaging·M Yavuz, J A Fessler
Dec 10, 1999·Physics in Medicine and Biology·H Erdogan, J A Fessler
Oct 6, 2000·IEEE Transactions on Medical Imaging·A V Bronnikov
Jan 1, 1992·IEEE Transactions on Medical Imaging·D S Lalush, B W Tsui
Jan 1, 1997·IEEE Transactions on Image Processing : a Publication of the IEEE Signal Processing Society·P CharbonnierM Barlaud

❮ Previous
Next ❯

Citations

Feb 5, 2016·Medical Physics·Yannick Berker, Yusheng Li
Aug 29, 2012·Zeitschrift für medizinische Physik·Axel Martinez-Möller, Stephan G Nekolla
Apr 1, 2007·PET Clinics·Habib ZaidiAbass Alavi
Sep 28, 2012·IEEE Transactions on Medical Imaging·Johan NuytsCharles Watson
Nov 23, 2006·NeuroImage·Habib ZaidiSteve Meikle
May 10, 2018·Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging·Lifang PangHongcheng Shi
Feb 9, 2016·Physics in Medicine and Biology·Ahmadreza RezaeiJohan Nuyts
Jun 6, 2015·Physics in Medicine and Biology·Abolfazl Mehranian, Habib Zaidi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.