Application of Dithiocarbamates as Potential New Antitrypanosomatids-Drugs: Approach Chemistry, Functional and Biological

Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry
Johny Wysllas de Freitas OliveiraMarcelo Sousa Silva

Abstract

Dithiocarbamates represent a class of compounds that were evaluated in different biomedical applications because of their chemical versatility. For this reason, several pharmacological activities have already been attributed to these compounds, such as antiparasitic, antiviral, antifungal activities, among others. Therefore, compounds that are based on dithiocarbamates have been evaluated in different in vivo and in vitro models as potential new antimicrobials. Thus, the purpose of this review is to present the possibilities of using dithiocarbamate compounds as potential new antitrypanosomatids-drugs, which could be used for the pharmacological control of Chagas disease, leishmaniasis, and African trypanosomiasis.

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Citations

Aug 13, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Peter A AjibadeNolwazi Solomane
Oct 18, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Nikolay I GorshkovEvgenii F Panarin
Nov 18, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Zhenbo YuanYijian Rao
Mar 30, 2021·Frontiers in Cellular and Infection Microbiology·Debbie-Ann ShirleyShannon Moonah
May 29, 2021·Scientific Reports·Johny Wysllas de Freitas OliveiraMarcelo Sousa Silva

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