Application of electrospun fibers for female reproductive health

Drug Delivery and Translational Research
Anna K BlakneyKim A Woodrow

Abstract

Here, we present the current challenges in women's reproductive health and the current state-of-the-art treatment and prevention options for STI prevention, contraception, and treatment of infections. We discuss how the versatile platform of electrospun fibers can be applied to each challenge, and postulate at how these technologies could be improved. The void of approved electrospun fiber-based products yields the potential to apply this useful technology to a number of medical applications, many of which are relevant to women's reproductive health. Given the ability to tune drug delivery characteristics and three-dimensional geometry, there are many opportunities to pursue new product designs and routes of administration for electrospun fibers. For each application, we provide an overview of the versatility of electrospun fibers as a novel dosage form and summarize their advantages in clinical applications. We also provide a perspective on why electrospun fibers are well-suited for a variety of applications within women's reproductive health and identify areas that could greatly benefit from innovations with electrospun fiber-based approaches.

References

Feb 1, 1994·American Journal of Public Health·L S CookK K Holmes
Dec 1, 1995·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·D C SokalT King
Dec 26, 2001·FEMS Immunology and Medical Microbiology·G ReidA W Bruce
Dec 26, 2001·The New England Journal of Medicine·B C TanisF R Rosendaal
May 7, 2002·Journal of Controlled Release : Official Journal of the Controlled Release Society·El-Refaie KenawyGary E Wnek
Sep 28, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Kimberly A Workowski, Stuart M Berman
Apr 11, 2003·Lancet·Jennifer S SmithValerie Beral
Apr 25, 2003·Journal of Controlled Release : Official Journal of the Controlled Release Society·Y K LuuM Hadjiargyrou
Apr 9, 2005·The Journal of Clinical Endocrinology and Metabolism·Jean-Patrice BaillargeonJohn E Nestler
Jul 12, 2005·Biomacromolecules·Sing Yian ChewKam W Leong
Aug 13, 2005·The Journal of Trauma·Stephen W RothwellEvelyn Sawyer
Aug 19, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Alfred DeMaria
Dec 24, 2005·Current Opinion in Infectious Diseases·Rebecca Pellett MadanBetsy C Herold
Oct 14, 2006·Mayo Clinic Proceedings·Chris KahlenbornWalter B Severs
Oct 17, 2006·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·N BölgenE Pişkin
Sep 22, 2007·Advanced Drug Delivery Reviews·Dehai LiangBenjamin Chu
Feb 19, 2008·Biomaterials·Travis J Sill, Horst A von Recum
Dec 18, 2008·JAMA : the Journal of the American Medical Association·Bridget M Kuehn
Aug 12, 2009·Proceedings of the National Academy of Sciences of the United States of America·Ying LiuDev Chidambaram
Aug 21, 2009·The Journal of School Health·Caroline W Kabiru, Pamela Orpinas
Oct 13, 2009·Biomacromolecules·Amparo López-RubioJose M Lagaron
Jan 15, 2010·Bulletin of the World Health Organization·Richard SteenFrancis Ndowa
Feb 9, 2010·Journal of Controlled Release : Official Journal of the Controlled Release Society·Haoqing CaoSing Yian Chew
Aug 4, 2010·American Journal of Reproductive Immunology : AJRI·Andrea R Thurman, Gustavo F Doncel
Jun 28, 2011·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Rabeea F Omar, Michel G Bergeron
Sep 28, 2006·Nanotechnology·W SalalhaE Zussman
Jul 23, 2011·Culture, Health & Sexuality·Chimaraoke O IzugbaraChibuogwu Izugbara
Jul 30, 2011·Indian Journal of Sexually Transmitted Diseases and AIDS·Smriti Naswa, Y S Marfatia
Jan 10, 2012·Dental Materials : Official Publication of the Academy of Dental Materials·Markus ReiseBernd W Sigusch
Dec 4, 2012·Current Opinion in HIV and AIDS·Catherine A Hankins, Mark R Dybul
Dec 5, 2012·PloS One·Cameron BallKim A Woodrow
Feb 14, 2013·Sexually Transmitted Diseases·Catherine Lindsey SatterwhiteHillard Weinstock
Mar 16, 2013·Mayo Clinic Proceedings·Mary L MarnachPetra M Casey

❮ Previous
Next ❯

Citations

May 13, 2020·Drug Development and Industrial Pharmacy·Fatmanur Tuğcu-DemirözFüsun Acartürk
Sep 13, 2017·Drug Delivery and Translational Research·David R Friend
May 8, 2021·Journal of Controlled Release : Official Journal of the Controlled Release Society·Rute NunesJosé das Neves

❮ Previous
Next ❯

Methods Mentioned

BETA
circumcision
contraception

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics
S Mehta
Diabetes Self-management
Monica J Smith
Medicine and Health, Rhode Island
Jennifer E Kacmar
© 2022 Meta ULC. All rights reserved