Application of FT-based MMSE deconvolution method for cerebral blood flow measurement in patients with leukoaraiosis.

Magnetic Resonance Imaging
Unal SakogluRohit Sood

Abstract

The bolus-tracking (BT) technique is the most popular perfusion-weighted (PW) dynamic susceptibility contrast MRI method used for estimating cerebral blood flow (CBF), cerebral blood volume and mean transit time. The BT technique uses a convolution model that establishes the input-output relationship between blood flow and the vascular tracer concentration. Singular value decomposition (SVD)- and Fourier transform (FT)-based deconvolution methods are popular and widely used for estimating PW MRI parameters. However, from the published literature, it appears that SVD is more widely accepted than other methods. In a previous article, an FT-based minimum mean-squared error (MMSE) technique was proposed and simulation experiments were performed to compare it with the well-established circular SVD (oSVD) method. In this study, the FT-based MMSE method has been used to estimate relative CBF (rCBF) in 13 patients with white matter lesions (WMLs) (leukoaraiosis), and results are compared with the widely used oSVD method. Thirteen patients with leukoaraiosis were imaged on a 1.5-T Siemens whole-body scanner. After acquiring the localizer and structural scans consisting of FLAIR (fluid attenuated with inversion recovery), T(1)-weighted a...Continue Reading

References

Feb 1, 1990·Archives of Neurology·M KobariM Ichijo
Nov 1, 1996·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·L OstergaardB R Rosen
Jun 20, 2003·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Ona WuA Gregory Sorensen
Nov 1, 1994·Physics in Medicine and Biology·G T Gobbel, J R Fike
Feb 3, 2007·Radiology·Elizabeth A SadowskiArjang Djamali
Jul 25, 2007·Cerebrovascular Diseases·Aaron M McMurtrayMario F Mendez
Dec 26, 2007·Magnetic Resonance Imaging·Unal Sakoglu, Rohit Sood

❮ Previous
Next ❯

Citations

Jun 26, 2010·Journal of Magnetic Resonance Imaging : JMRI·Jinsoo UhHanzhang Lu

❮ Previous
Next ❯

Related Concepts

Related Feeds

Aphasia

Aphasia affects the ability to process language, including formulation and comprehension of language and speech, as well as the ability to read or write. Here is the latest research on aphasia.

Related Papers

Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine
Fernando CalamanteAlan Connelly
Dementia and Geriatric Cognitive Disorders
Noriyuki KimuraToshihide Kumamoto
Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism
Masanobu IbarakiIwao Kanno
© 2021 Meta ULC. All rights reserved