PMID: 8994397Dec 1, 1996Paper

Application of meta-analysis in reviewing occupational cohort studies

Occupational and Environmental Medicine
O Wong, G K Raabe

Abstract

Meta-analysis has been used increasingly in reviewing and summarising epidemiological studies. Reviews incorporating meta-analyses have appeared in medical journals in increasing numbers. Although there are several methodology papers on meta-analysis, most of these papers have been written primarily for discussion among epidemiologists. The present paper considers some of the basic methodological issues, the more practical aspects of meta-analysis, and targets an audience of mainly non-epidemiologists. Thus, the main objective of this paper is to provide some basic guidelines for non-epidemiologists to evaluate meta-analysis in occupational cohort studies. In this methodology paper, the limitations and problems of traditional qualitative reviews are pointed out. Some of these problems can be dealt with by quantitative meta-analysis. The potential limitations and benefits of quantitative meta-analysis are discussed. Rather than replacing traditional qualitative review, quantitative meta-analysis should be made part of the overall assessment. The term "meta-review" is proposed to emphasise the importance of both qualitative and quantitative components in a comprehensive review process. The basic steps in a meta-review are outline...Continue Reading

References

Jan 1, 1992·Epidemiologic Reviews·K Dickersin, J A Berlin
Jan 1, 1985·Medical and Pediatric Oncology·J C NunninkJ W Yates
Apr 1, 1987·Statistics in Medicine·R Peto
Jan 1, 1987·Epidemiologic Reviews·S Greenland
Apr 1, 1985·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·R W Morgan, O Wong
Nov 1, 1981·Journal of Learning Disabilities·K A Kavale, G V Glass
Jun 1, 1994·Journal of Medical Systems·K AkazawaY Nose
Aug 1, 1994·American Journal of Epidemiology·S Greenland
Jun 2, 1993·JAMA : the Journal of the American Medical Association·D J CookA D Oxman

❮ Previous
Next ❯

Citations

Jan 30, 2007·Occupational and Environmental Medicine·Adam Simning, Edwin van Wijngaarden
Apr 16, 1998·Occupational and Environmental Medicine·M KogevinasS Hoar-Zahm
Sep 26, 2007·Archives of Environmental & Occupational Health·Sami Youakim
Jan 20, 1998·Drug and Chemical Toxicology·E A MaullS P Sorgen
Feb 25, 2006·Regulatory Toxicology and Pharmacology : RTP·R Alexandra GoldbohmE Dinant Kroese
Mar 21, 1998·Journal of Occupational and Environmental Medicine·L I GardnerB W Koes
Nov 14, 2006·Journal of Occupational and Environmental Medicine·Grace K LeMastersJames Lockey
Nov 21, 1998·Cancer Detection and Prevention·R Chen, A Seaton

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.