Application of minimal important differences in degenerative knee disease outcomes: a systematic review and case study to inform BMJ Rapid Recommendations

BMJ Open
Tahira DevjiPer O Vandvik

Abstract

To identify the most credible anchor-based minimal important differences (MIDs) for patient important outcomes in patients with degenerative knee disease, and to inform BMJ Rapid Recommendations for arthroscopic surgery versus conservative management DESIGN: Systematic review. Estimates of anchor-based MIDs, and their credibility, for knee symptoms and health-related quality of life (HRQoL). MEDLINE, EMBASE and PsycINFO. We included original studies documenting the development of anchor-based MIDs for patient-reported outcomes (PROs) reported in randomised controlled trials included in the linked systematic review and meta-analysis and judged by the parallel BMJ Rapid Recommendations panel as critically important for informing their recommendation: measures of pain, function and HRQoL. 13 studies reported 95 empirically estimated anchor-based MIDs for 8 PRO instruments and/or their subdomains that measure knee pain, function or HRQoL. All studies used a transition rating (global rating of change) as the anchor to ascertain the MID. Among PROs with more than 1 estimated MID, we found wide variation in MID values. Many studies suffered from serious methodological limitations. We identified the following most credible MIDs: Wester...Continue Reading

Citations

Feb 17, 2018·British Journal of Sports Medicine·Reed A C SiemieniukAnnette Kristiansen
Sep 5, 2018·Clinical Orthopaedics and Related Research·Nicholas D ClementDavid J Deehan
Apr 11, 2019·Annual Review of Biomedical Engineering·Caroline A MurphyMaurice N Collins
Jun 20, 2019·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Juan J Amer-CuencaJosué Fernández-Carnero
Feb 24, 2019·British Journal of Sports Medicine·Simon G F AbramAndrew J Price
Aug 29, 2020·British Journal of Sports Medicine·Raine SihvonenUNKNOWN FIDELITY (Finnish Degenerative Meniscus Lesion Study) Investigators
Jul 27, 2018·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Christopher SmithMohit Bhandari
Jun 29, 2018·Medicine·Eleuterio A Sánchez-RomeroJosué Fernández-Carnero
May 19, 2019·BMC Musculoskeletal Disorders·Paola SivieroUNKNOWN EPOSA Research Group
Aug 5, 2020·Archives of Orthopaedic and Trauma Surgery·Antonio KlasanDavid A Parker
Jan 23, 2020·International Journal of Environmental Research and Public Health·Patricia Palomo-LópezVictoria Mazoteras-Pardo
Jul 7, 2017·Nature Reviews. Rheumatology·Teppo L N Järvinen, Gordon H Guyatt
Mar 20, 2019·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Eleuterio A Sánchez RomeroDaniel Pecos-Martín
Jan 5, 2019·The American Journal of Sports Medicine·Julia C A NoorduynUNKNOWN ESCAPE Research Group
Dec 16, 2020·Journal of Clinical Epidemiology·Alonso Carrasco-LabraGordon H Guyatt
Jan 16, 2021·The Journal of Bone and Joint Surgery. American Volume·Evan M FarinaElizabeth G Matzkin
Apr 7, 2020·Journal of Shoulder and Elbow Surgery·Ian A JonesC Thomas Vangsness
Mar 12, 2021·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Lee YaariBarak Haviv
Mar 26, 2021·BMC Medical Research Methodology·Lauri RaittioAleksi Reito
Mar 16, 2021·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·Andreas H GomollKatie C Mowry
Oct 17, 2020·Scandinavian Journal of Medicine & Science in Sports·Jonathan David CominsMichael R Krogsgaard
Jul 29, 2021·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Andrew Trigg, Philip Griffiths
Sep 12, 2021·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·Mikko UimonenAleksi Reito
Jun 7, 2021·American Journal of Physical Medicine & Rehabilitation·Susan Armijo-OlivoJorge Fuentes

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.