PMID: 7796237May 1, 1995Paper

Application of nasal continuous positive airway pressure to early extubation in very low birthweight infants

Archives of Disease in Childhood. Fetal and Neonatal Edition
B H SoS Kamoshita

Abstract

Using a preset protocol for early extubation, 50 babies were randomly selected to post-extubation headbox or post-extubation nasal continuous positive airway pressure (N-CPAP). All infants weighed less than 1500 g, had a gestational age of less than 34 weeks, and had been weaning from mechanical ventilation within seven days of life. The criteria for extubation included stable condition, fraction of inspired oxygen (FIO2) of < or = 35%, peak inspiratory pressure (PIP) of < or = 15 cm H2O (1.47 kPa), and ventilator rate of 6/minute. Before extubation, a loading dose of aminophylline was given followed by maintenance treatment. If reintubation was not required within 72 hours of the initial extubation the procedure was considered successful. The reintubation criteria included FIO2 > or = 70% to maintain arterial oxygen tension (PaO2) of > or = 50 mm Hg (6.67 kPa) or pulse oximetry between 90-96% and pH of < 7.25, and arterial carbon dioxide tension (PACO2) of > 60 mm Hg (8.00 kPa) and severe or recurring apnoea. The overall success rate of early extubation was 66% (33/50). The individual successful extubation rate of post-extubation in the N-CPAP group and the post-extubation headbox group were 84% (21/25) and 48% (12/25), respec...Continue Reading

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Citations

Jul 1, 1997·Acta Paediatrica. Supplement·N W SvenningsenM Lindroth
Sep 1, 1996·Archives of Disease in Childhood. Fetal and Neonatal Edition·S K Sinha, S M Donn
Nov 3, 1998·Archives of Disease in Childhood. Fetal and Neonatal Edition·P DavisP Henschke
Nov 3, 1998·Archives of Disease in Childhood. Fetal and Neonatal Edition·N J Robertson, P A Hamilton
Nov 3, 1998·Archives of Disease in Childhood. Fetal and Neonatal Edition·M van der HoevenC E Blanco
Aug 17, 1999·Archives of Disease in Childhood. Fetal and Neonatal Edition·C Morley
Jun 29, 2000·Archives of Disease in Childhood. Fetal and Neonatal Edition·S K Sinha, S M Donn
Dec 17, 2011·European Journal of Pediatrics·Olie ChowdhuryAnne Greenough
Sep 23, 2014·Early Human Development·Sandeep Shetty, Anne Greenough
Mar 31, 2007·Clinics in Perinatology·Sherry E Courtney, Keith J Barrington
May 27, 2011·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Christoph CzernikHans Proquitté
Jul 30, 2002·Neonatal Network : NN·S K Berends
Jun 30, 2004·Blood Cells, Molecules & Diseases·Selena Trajkovic-BodennecAnthony H Futerman
Dec 18, 2001·Pediatric Pulmonology·M VarugheseJ Whitehall
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Jan 30, 2009·Neonatal Network : NN·Amanda Jayne Squires, Marilyn Hyndman
Jul 28, 2016·Neonatal Network : NN·Lina Kurdahi BadrLama Charafeddine
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