PMID: 7796237May 1, 1995Paper

Application of nasal continuous positive airway pressure to early extubation in very low birthweight infants

Archives of Disease in Childhood. Fetal and Neonatal Edition
B H SoS Kamoshita


Using a preset protocol for early extubation, 50 babies were randomly selected to post-extubation headbox or post-extubation nasal continuous positive airway pressure (N-CPAP). All infants weighed less than 1500 g, had a gestational age of less than 34 weeks, and had been weaning from mechanical ventilation within seven days of life. The criteria for extubation included stable condition, fraction of inspired oxygen (FIO2) of < or = 35%, peak inspiratory pressure (PIP) of < or = 15 cm H2O (1.47 kPa), and ventilator rate of 6/minute. Before extubation, a loading dose of aminophylline was given followed by maintenance treatment. If reintubation was not required within 72 hours of the initial extubation the procedure was considered successful. The reintubation criteria included FIO2 > or = 70% to maintain arterial oxygen tension (PaO2) of > or = 50 mm Hg (6.67 kPa) or pulse oximetry between 90-96% and pH of < 7.25, and arterial carbon dioxide tension (PACO2) of > 60 mm Hg (8.00 kPa) and severe or recurring apnoea. The overall success rate of early extubation was 66% (33/50). The individual successful extubation rate of post-extubation in the N-CPAP group and the post-extubation headbox group were 84% (21/25) and 48% (12/25), respec...Continue Reading


Feb 6, 1975·The New England Journal of Medicine·P M SuterM D Isenberg
Nov 1, 1979·The Journal of Pediatrics·J T WungL S James
Jun 1, 1992·Acta Paediatrica Japonica; Overseas Edition·B H SoS Kamoshita
Dec 1, 1990·International Journal of Pediatric Otorhinolaryngology·D M AlbertJ N Thomas
Jan 1, 1990·Pediatric Pulmonology·M J BalsanR D Guthrie
Jan 1, 1990·Pediatric Pulmonology·K A Veness-MeehanJ M Davis
May 1, 1973·Archives of Disease in Childhood·J A Kuzemko, J Paala
Jun 1, 1983·Critical Care Medicine·L L FanD R Pathak
Apr 1, 1982·American Journal of Diseases of Children·S C EngelkeL R Kuhns
May 1, 1993·Archives of Disease in Childhood·V Chan, A Greenough
Jan 1, 1993·Pediatric Radiology·J C OditaA Ammari

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