Application of power spectra patterns in Fourier transform square wave voltammetry to evaluate electrode kinetics of surface-confined proteins.

Analytical Chemistry
Barry D FlemingF A Armstrong

Abstract

This paper describes an application of Fourier transform (FT) voltammetry that provides a quantitative evaluation of the electron-transfer kinetics of protein molecules attached to electrode surfaces. The potential waveform applied in these experiments consists of a large-amplitude square wave of frequency f superimposed onto the traditional triangular voltage used in dc cyclic voltammetry. The resultant current-time response, when Fourier transformed into the frequency domain, provides patterns of data at the even harmonic frequencies that arise from nonlinearity in the Faradaic response. These even harmonic contributions are ideally suited for kinetic evaluation of electron-transfer processes because they are highly selective to quasi-reversible behavior (insensitive to reversible or irreversible processes) and almost devoid of background charging current. Inverse FT methods can then be used to provide the wave shapes of the dc as well as the ac voltammetric components and other characteristics employed to detect the level of nonideality present relative to theoretical models based upon noninteracting surface-confined molecules. The new form of data evaluation has been applied to the electron-transfer properties of a typical ...Continue Reading

Citations

Nov 13, 2015·Proceedings of the National Academy of Sciences of the United States of America·Hope AdamsonAlison Parkin
Aug 15, 2017·Chemical Communications : Chem Comm·Hope AdamsonAlison Parkin
Oct 25, 2013·Chemical Communications : Chem Comm·Christopher F Blanford
Nov 29, 2007·Langmuir : the ACS Journal of Surfaces and Colloids·Barry D FlemingLisandra L Martin
Sep 10, 2010·Analytical Chemistry·Andrzej S Baranski, Aliaksei Boika
Nov 12, 2010·Journal of the American Chemical Society·Amol Virendra Patil, Jason John Davis
Nov 14, 2019·Analytical Chemistry·Valentin MirceskiRubin Gulaboski
Aug 30, 2007·Analytical Chemistry·Joaquín GonzálezMarién M Moreno
Sep 30, 2006·Analytical Chemistry·Costas A AnastassiouDanny O'Hare
Jul 16, 2008·Chemical Reviews·Christophe Léger, Patrick Bertrand

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