Application of resequencing microarrays in microbial detection and characterization

Future Microbiology
Tomasz A LeskiDavid A Stenger

Abstract

Microarrays are powerful, highly parallel assays that are transforming microbiological diagnostics and research. The adaptation of microarray-based resequencing technology for microbial detection and characterization resulted in the development of a number assays that have unique advantages over other existing technologies. This technological platform seems to be especially useful for sensitive and high-resolution multiplexed diagnostics for clinical syndromes with similar symptoms, screening environmental samples for biothreat agents, as well as genotyping and whole-genome analysis of single pathogens.

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Methods Mentioned

BETA
chip
genotyping
nucleic acid amplification
PCR
MDA

Software Mentioned

Flu
Affymetrix
NimbleGen
TEI
RPM
Virochip

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