Application of response surface methodology in optimization of electrospinning process to fabricate (ferrofluid/polyvinyl alcohol) magnetic nanofibers

Materials Science & Engineering. C, Materials for Biological Applications
Mohaddeseh AhmadipourroudposhtAni Idris

Abstract

Magnetic nanofibers are composed of good dispersion of magnetic nanoparticles along an organic material. Magnetic nanofibers are potentially useful for composite reinforcement, bio-medical and tissue engineering. Nanofibers with the thinner diameter have to result in higher rigidity and tensile strength due to better alignments of lamellae along the fiber axis. In this study, the performance of electrospinning process was explained using response surface methodology (RSM) during fabrication of magnetic nanofibers using polyvinyl alcohol (PVA) as a shelter for (γ-Fe2O3) nanoparticles where the parameters investigated were flow rate, applied voltage, distance between needle and collector and collector rotating speed. The response variable was diameter distribution. The two parameters flow rate and applied voltage in primary evaluation were distinguished as significant factors. Central composite design was applied to optimize the variable of diameter distribution. Quadratic estimated model developed for diameter distribution indicated the optimum conditions to be flow rate of 0.25 ml/h at voltage of 45 kV while the distance and rotating speed are at 8 cm and 1500 rps respectively. The obtained model was verified successfully by th...Continue Reading

References

Jul 21, 2004·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Dhirendra S KattiCato T Laurencin
Nov 24, 2004·Colloids and Surfaces. B, Biointerfaces·Kalpana S Katti
Apr 30, 2009·Materials Science & Engineering. C, Materials for Biological Applications·Vince Beachley, Xuejun Wen
Jun 12, 2012·Journal of Hazardous Materials·Ani IdrisChan Eng Seng
Oct 8, 2013·Materials Science & Engineering. C, Materials for Biological Applications·Melika SaremV Prasad Shastri
May 27, 2014·Materials Science & Engineering. C, Materials for Biological Applications·Olga G Cisneros-PinedaJosé M Cervantes-Uc
Jan 13, 2015·Materials Science & Engineering. C, Materials for Biological Applications·Ehsan FallahiarezoudarNoordin Mohd Yusof

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Citations

Dec 15, 2015·Materials Science & Engineering. C, Materials for Biological Applications·Peiyun YiJiaqiang Huang
Oct 25, 2016·Materials Science & Engineering. C, Materials for Biological Applications·Nor Hasrul Akhmal NgadimanDenni Kurniawan
Apr 8, 2017·Frontiers in Bioengineering and Biotechnology·Monia OrcianiMonica Mattioli-Belmonte
Sep 5, 2020·Biomedical Engineering Online·Marjan Bahraminasab

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