Application of Single-cell RNA Sequencing in Research on Tumor Immune Microenvironment

Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae
Kai Li YangLin Zhao

Abstract

Tumors are highly complex systems. Understanding the compositions and functions of the tumor immune microenvironment is a prerequisite for effective tumor immunotherapy. Single-cell RNA sequencing can detect the transcriptome of a cell at the resolution of single-cell level,describe its functional status,and thus deepen the understanding of the composition and function of different cell clusters in tumor immune microenvironment. This article reviews the application of single-cell RNA sequencing in research on tumor immune microenvironment.

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