Application of statistical design for the optimization of microbial community of synthetic domestic wastewater

Biodegradation
Yuancai ChenHuaiyu Zhan

Abstract

A fractional factorial design (FFD) and a response surface methodology (RSM) were used to optimize the inoculum composition of six strains for treatment of synthetic domestic wastewater. The model predicted the highest overall specific substrate utilization rate (q) of 6.88 g TOC/(d-gVSS). The value is in accordance with the actual maximum q, and is 1.5 and 1.97 times greater than those without optimization for 4 and 6 strains respectively. Additionally, the shortest time to reach stationary phase (3.5 h) and highest maximum total organic carbon (TOC) removal efficiency (92%) were also achieved under the optimum condition. The results indicated that the FFD and RSM are powerful screening and optimizing tools for the microbial community. The experimental approaches enhance the overall specific rate of substrate utilization as well as other biodegradation parameters.

References

Jul 10, 2003·Current Opinion in Biotechnology·Aurelio Briones, Lutgarde Raskin
Jan 22, 2005·Trends in Biotechnology·Andrew C SingerIan P Thompson
Jun 9, 2005·Current Opinion in Microbiology·Saïd El Fantroussi, Spiros N Agathos
Jun 11, 2005·Environmental Microbiology·Ian P ThompsonAndrew C Singer
Mar 21, 2007·Applied Microbiology and Biotechnology·He-Long JiangJoo-Hwa Tay
Mar 10, 2009·Nature·Lieven WittebolleNico Boon
Jul 28, 2009·Journal of Hazardous Materials·Yuancai ChenHuaiyu Zhan

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Citations

Apr 6, 2019·Current Opinion in Biotechnology·Alexander Eng, Elhanan Borenstein

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