Application of the BAR score as a predictor of short- and long-term survival in liver transplantation patients

Hepatology International
Ivan Dias de Campos JuniorIlka de Fátima Santana Ferreira Boin

Abstract

The balance of risk (BAR) is a prediction system after liver transplantation. To assess the BAR system, a retrospective observational study was performed in 402 patients who had transplant surgery between 1997 and 2012. The BAR score was computed for each patient. Receiver operating characteristic curve analysis with the Hosmer-Lemeshow test was used to calculate sensitivity, specificity, and model calibration. The cutoff value with the best Youden index was selected. Statistical analysis employed the Kaplan-Meier method (log-rank test) for survival, the Mann-Whitney test for group comparison, and multiple logistic regression analysis. 3-month survival was 46% for BAR ≥ 11 and 77% for BAR <11 (p = 0.001); 12-month survival was 44% for BAR ≥ 11 and 69% for BAR <11 (p = 0.001). Factors of survival <3 months were BAR ≥ 11 [odds ratio (OR) 3.08; 95% confidence interval (CI) 1.75-5.42; p = 0.001] and intrasurgical use of packed red blood cells (RBC) above 6 units (OR 4.49; 95% CI 2.73-7.39; p = 0.001). For survival <12 months, factors were BAR ≥ 11 (OR 2.94; 95% CI 1.67-5.16; p = 0.001) and RBC >6 units (OR 2.99; 95% CI 1.92-4.64; p = 0.001). Our study contributes to the incorporation of the BAR system into Brazilian transplantation...Continue Reading

References

Feb 2, 1999·Archives of Surgery·T V CacciarelliC O Esquivel
Mar 25, 2000·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·M MalinchocP C ter Borg
Dec 9, 2000·Transplant International : Official Journal of the European Society for Organ Transplantation·H PokornyR Steininger
Feb 15, 2001·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·P S KamathW R Kim
Mar 23, 2002·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Robert S BrownJean C Emond
Apr 20, 2002·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Kelly W BurakMichael R Charlton
Aug 23, 2002·Annals of Surgery·Rafik M GhobrialRonald W Busuttil
Jan 4, 2003·Gastroenterology·Russell WiesnerUNKNOWN United Network for Organ Sharing Liver Disease Severity Score Committee
Nov 20, 2003·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Emilio RamosEduardo Jaurrieta
Jan 31, 2004·Transplantation·Lisa M Forman, Michael R Lucey
Apr 16, 2004·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·K V Narayanan MenonRussell H Wiesner
Jun 15, 2004·Transplantation Proceedings·M B RochaL S Leonardi
Nov 24, 2004·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Manish G AminJohn B Wong
Jun 24, 2005·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Matthew JacobJan H P van der Meulen
Jul 9, 2005·European Journal of Gastroenterology & Hepatology·Evi NaglerBernard de Hemptinne
Feb 25, 2006·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Shahid HabibA Obaid Shakil
Mar 17, 2006·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·S FengR M Merion
May 6, 2008·Transplantation Proceedings·I F S F BoinL Sergio Leonardi
May 6, 2008·Transplantation Proceedings·I F S F BoinL S Leonardi
Sep 12, 2008·Gastroenterología y hepatología·Isabel Campos-Varela, Lluís Castells
Oct 24, 2008·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·A RanaJ C Emond
Dec 19, 2008·Critical Care : the Official Journal of the Critical Care Forum·Lilian MinneEvert de Jonge
Jan 6, 2009·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·J B HalldorsonJ D Perkins
Jan 28, 2010·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Chung-Shun WongYung-Chang Chen
Mar 30, 2011·Canadian Journal of Surgery. Journal Canadien De Chirurgie·Dionisios VrochidesPeter Metrakos

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Citations

Jul 20, 2019·Transplantation Direct·Jacob D de BoerAndries E Braat
Dec 26, 2018·World Journal of Gastroenterology : WJG·Thierry ArtznerFrançois Faitot
Jun 17, 2021·Arquivos Brasileiros De Cirurgia Digestiva : ABCD = Brazilian Archives of Digestive Surgery·Fernando TorterolliOsvaldo Malafaia

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